Cloud computing platform-based interactive analysis system and method for transcriptome project with reference genome

Abstract

The invention discloses a cloud computing platform-based interactive analysis system and method for a transcriptome project with a reference genome. In a project management module, sequencing data is uploaded to a local cluster server after an analysis project is established; a private reference genome database of a user is uploaded or a public database configured in a platform is selected according to an actual demand; and the user locks the project in the module or selectively shares the project to others for operation and management. In a basic analysis task submitting module, the user performs parameter setting and calculation analysis on the sequencing data in a visual interface; before the calculation analysis, whether data quality control meets standardized requirements or not is prejudged; if the requirements are not met, error report information is directly returned; if the requirements are met, the calculation analysis of specified parameters is carried out; a corresponding project file is generated after the calculation analysis; the project file is transmitted to an interactive result analysis module for performing interactive analysis; and an intuitive standardized report is generated.

Description

technical field [0001] The invention relates to the technical field of biological information analysis, in particular to an interactive analysis system and method for a transcriptome project with a reference genome based on a cloud computing platform. Background technique [0002] Transcriptome refers to the collection of all RNAs transcribed in a certain species, tissue or cell in a specific state, including mRNA and non-coding RNA. Transcriptome is the link between the genome that bears genetic material and the proteome that performs biological functions. The regulation of transcription level is the most important and widely studied regulation method. Compared with the study of genome level, transcriptome research can give more efficient results. More precise research information. [0003] Although high-throughput sequencing technology has made great progress compared with traditional sequencing technology, deciphering animal and plant genomes still faces great difficulti...

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Problems solved by technology

[0007] Aiming at the deficiencies in the above-mentioned technologies, the present invention provides an interactive analysis system and method for transcriptome projects with reference genomes based on a cloud computing platform to solve the problems of large data processing and analysis that cannot be completed by personal computers and workstations. The problem of low efficiency of the existing manual business process

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