A galanthamine hydrobromide tablet

A galantamine hydrobromide tablet and a technology of galantamine hydrobromide, which are applied in the fields of pill delivery, inorganic non-active ingredients, nervous system diseases, etc., can solve the problem of easy moisture absorption of tablets and the content of batches of products Inhomogeneity, affecting the development and application of preparations, etc., to achieve stable quality, solve the problem of easily absorbing water, and solve the problem of content uniformity

Inactive Publication Date: 2018-03-02
WEIHAI GUANBIAO INFORMATION TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

During the preparation of oral solid preparations, it was found that, firstly, there was uneven content between batches of products,

Method used

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Abstract

The invention relates to a galantamine composition and belongs to the technical field of pharmaceutical preparations. The technical scheme of the present invention is: a kind of galanthamine hydrobromide tablet, in the tablet of unit dose, containing D90 is the galantamine hydrobromide 4-5mg of 20um, calcium hydrogen phosphate dihydrate 40-5mg 70mg, carmellose sodium 2‑8mg, chitosan 6‑14mg, microcrystalline cellulose 60‑110mg, magnesium stearate 1‑2mg. The invention provides a stable galantamine tablet.

Description

technical field [0001] The invention relates to a galantamine composition and belongs to the technical field of pharmaceutical preparations. Background technique [0002] Alzheimer's disease, also known as senile dementia, is a common senile neurodegenerative disease, clinically manifested as cognitive, language and behavioral dysfunction. With the increasingly serious phenomenon of population aging, AD has become another "killer" that threatens human health after cardiovascular and cerebrovascular diseases, malignant tumors, and stroke. Alzheimer's disease occupies an important position in the senile disease spectrum and the death spectrum, which seriously threatens the health, longevity and quality of life of the elderly. It has brought a serious burden to patients themselves, their families and society. [0003] Galantamine is an acetylcholinease inhibitor. Galantamine is unstable in air and is usually made into hydrobromide. Galantamine, as an anti-AD drug, was approv...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/55A61K47/38A61K47/36A61K47/02A61P25/28
CPCA61K31/55A61K9/2009A61K9/205A61K9/2054
Inventor 孙爱梅
Owner WEIHAI GUANBIAO INFORMATION TECH
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