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A fat-soluble glabridin compound whitening agent and its application

A glabridin and fat-soluble technology, which is applied in pharmaceutical formulas, cosmetic preparations, skin care preparations, etc., can solve problems such as consumer allergies, freckle cosmetics with little effect, mercury poisoning, etc., to prevent melanin precipitation, Promotes the differentiation of melanocytes and delays skin oxidation

Active Publication Date: 2021-07-09
亿利耐雀生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Almost all freckle-removing cosmetics have little effect, and some unscrupulous merchants even add large doses of toxic and harmful substances such as hydroquinone, hormones, or aminomercuric chloride to cosmetics for the purpose of freckle-removing, causing severe allergies or mercury poisoning to some consumers

Method used

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  • A fat-soluble glabridin compound whitening agent and its application
  • A fat-soluble glabridin compound whitening agent and its application
  • A fat-soluble glabridin compound whitening agent and its application

Examples

Experimental program
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Effect test

Embodiment 1

[0035] Embodiment 1: Weigh 40% Glycyrrhizae glabra extract, 20% tetrahydroxychalcone, 20% ubiquinone and 20% endothelin antagonist by mass parts, grind each component, and grind the mixture 100 mesh sieve to obtain fat-soluble glabridin compound whitening agent.

Embodiment 2

[0036] Embodiment 2: Weigh 45% Glycyrrhiza glabra extract, 15% tetrahydroxychalcone, 25% ubiquinone and 15% endothelin antagonist by mass parts, grind each component, and pass the pulverized mixture 100 mesh sieve to obtain fat-soluble glabridin compound whitening agent.

Embodiment 3

[0037] Embodiment 3: Weigh 35% Glycyrrhizae glabra extract, 25% tetrahydroxychalcone, 15% ubiquinone and 25% endothelin antagonist by mass parts, grind each component, and grind the mixture 100 mesh sieve to obtain fat-soluble glabridin compound whitening agent.

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Abstract

The invention discloses a fat-soluble glabridin compound whitening agent and its application in cosmetics. The compound whitening agent comprises the following active components in weight percent: 30-50% glabra extract, 10-30% tetrahydroxy Chalcone, 10‑30% ubiquinone and 10‑30% endothelin antagonist. The main whitening mechanism of the compound whitening agent prepared by the present invention is to inhibit the activity of tyrosinase, inhibit the activity of DOPA pigment tautomerase and hinder the polymerization of lndole-5,6-quinone, thereby blocking the generation of melanin , and reduce the differentiation of melanocytes to achieve the purpose of whitening and lightening spots and improving dull skin tone. The formula of the invention is simple and practical, has good effect of whitening and lightening spots, and adopts natural products, is green and safe, mild and non-irritating when used, and overcomes the shortcomings of existing whitening agents.

Description

technical field [0001] The invention relates to a cosmetic formulation, in particular to a fat-soluble glabridin compound whitening agent and an application thereof. Background technique [0002] The uneven distribution and accumulation of melanocytes on the surface of the skin can lead to dull skin and dark spots. The main pathway leading to the formation of melanin is that tyrosinase converts tyrosine into dopa, which is further oxidized into dopaquinone, and finally forms melanin. Over the years, the cosmetics industry has been constantly seeking technological breakthroughs and is committed to developing safe and efficient whitening ingredients. [0003] Currently common whitening mechanisms and raw materials include: inhibiting tyrosinase activity, such as glutathione and glabridin; complexing copper ions to prevent DHI polymerization, such as phytic acid, kojic acid and their derivatives; reducing melanin, such as VC and its derivatives; accelerate the degradation of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/35A61Q19/02
CPCA61K8/35A61K8/355A61K2800/592A61K2800/5922A61K2800/782A61Q19/02A61K8/9789
Inventor 魏元刚刘亿宁杨永安钟慧左婧
Owner 亿利耐雀生物科技有限公司
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