Magnetic particle field current separating device and method based on rotating magnetic field
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A magnetic particle and field flow separation technology, applied in magnetic separation, chemical instruments and methods, solid separation, etc., can solve problems such as low precision and difficult implementation
Active Publication Date: 2019-02-22
DALIAN JIAOTONG UNIVERSITY
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This rotating magnetic field changes the frequency of action of the magnetic field on the magnetic particles in the separation channel by adjusting the motor speed, and the accuracy is not high
To change the magnetic induction intensity in the separation channel, it is necessary to adjust the distance between the magnet and the separation channel, and it is difficult to ensure the parallelism between the rotation track of the magnet and the separation channel.
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Embodiment 1
[0047] Such as Figure 1-Figure 6 As shown, a magnetic particle field flow separation device based on a rotating magnetic field, including a three-phase winding 2;
[0048] The three-phase winding 2 includes a first phase winding, a second phase winding and a third phase winding;
[0049] The first phase winding, the second phase winding and the third phase winding are star-connected and arranged on the base 1 axisymmetrically with the axis of the base 1;
[0050] The base 1 is a cast iron base;
[0051] The head end U of the first phase winding, the second phase winding and the third phase winding 1 , V 1 , W 1 Respectively with the output terminal L of the three-phase power supply 1 , L 2 , L 3 connected, the output current of the three-phase power supply is a symmetrical three-phase sinusoidal alternating current;
[0052] The base 1 is a hollow structure, and a separation channel is provided in the space surrounded by it;
[0053] The input end of the separation c...
Embodiment 2
[0067] A method for magnetic particle field flow separation based on the magnetic particle field flow separation device described in embodiment 1, has the following steps:
[0068] S1. The three-phase power supply inputs current i to the first phase winding, the second phase winding and the third phase winding respectively U i V i W , forming a rotating magnetic field in the space surrounded by the base 1, and adjusting the frequency of the rotating magnetic field and the voltage on the three-phase winding through the frequency converter 5;
[0069] S2. When the thickness of the plastic cylinder is constant, by changing the diameter of the inner wall and the diameter of the outer wall of the plastic cylinder, the radial position of the microtube is adjusted, and the magnetic induction intensity at the position of the separation channel is changed;
[0070] S3, the magnetic particles with different magnetic susceptibilities injected through the injection syringe 8 and the mob...
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Abstract
The invention discloses a magnetic particle field current separating device and method based on a rotating magnetic field. The device comprises a three-phase winding which comprises a first phase winding, a second phase winding and a third phase winding. The first phase winding, the second phase winding and the third phase winding are connected in a star shape and are symmetrically arranged on a base with the axis of the base as a shaft. The initial ends of the first phase winding, the second phase winding and the third phase winding communicate with the output end of a three-phase power source. Output current of the three-phase power source is symmetrical three-phase sine alternating current. The base is of a hollow structure, and a separation channel is formed in a space designed by thebase. According to the magnetic particle field current separating device, the separation channel is arranged in the internal cylindrical space defined by the three-phase winging and the base, and magnitude and frequency of three-phase voltage added to the three-phase winding are adjusted through a frequency converter. The frequency of magnetic particles affected by the rotating magnetic field is controlled, the magnitude of magnetic induction intensity of the separation channel is changed, and filed current separation of the magnetic particles with different particle diameters or magnetic particles which are the same in particle diameter but different in magnetic susceptibility.
Description
technical field [0001] The invention relates to the field of magnetic particle analysis and separation, in particular to a magnetic particle field flow separation device and method based on a rotating magnetic field. Background technique [0002] Magnetic particles have broad application prospects in the fields of magnetic drug manufacturing, magnetic resonance imaging, magnetic hyperthermia, and cell screening. The research on magnetic particles and microspheres has greatly promoted the development of biomedicine. [0003] In the application process of magnetic particles, it is required to have good monodispersity. The monodispersity of the magnetic particles refers to the uniformity of the particle diameter and the uniformity of the magnetic susceptibility. It is still difficult to obtain magnetic particles with good monodispersity by optimizing the process conditions during the preparation of magnetic particles, and further separation and screening of the prepared magnet...
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