Gene sequencing library preparation device

A technology for gene sequencing and preparation devices, which is applied in chemical libraries, biochemical cleaning devices, enzymology/microbiology devices, etc., can solve problems such as high professional skills requirements, long time-consuming, complicated operations, etc., to avoid experimental errors and improve Operational efficiency and the effect of reducing the probability of errors

Active Publication Date: 2019-03-15
3D BIOMEDICINE SCI & TECH CO LTD
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Library preparation is a key factor in Illumina's integrated sequencing workflow. This step is complex, time-consuming, and requires high professional skills for operators

Method used

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  • Gene sequencing library preparation device
  • Gene sequencing library preparation device
  • Gene sequencing library preparation device

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Embodiment Construction

[0057] While the present invention will be fully described with reference to the accompanying drawings containing preferred embodiments of the invention, it should be understood before proceeding that those skilled in the art may modify the invention described herein while obtaining the technical effects of the present invention. Therefore, it should be understood that the above description is a broad disclosure for those skilled in the art, and its content is not intended to limit the described exemplary embodiments of the present invention.

[0058] In addition, in the following detailed description, for purposes of explanation, numerous specific details are set forth in order to provide a comprehensive understanding of the embodiments of the present disclosure. It may be evident, however, that one or more embodiments may be practiced without these specific details. In other instances, well-known structures and devices are shown in diagrammatic form to simplify the drawings....

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Abstract

The invention belongs to the technical field of gene sequencing and particularly discloses a gene sequencing library preparation device. The device comprises a card case holding unit, a card case locking unit, a liquid supply drive unit, a card case rotation drive unit and a controller, wherein the card case holding unit comprises a holding support and a holding groove located on the holding rackand used for holding a card case; the card case locking unit is used for locking the card case in the holding groove; the liquid supply driving unit comprises a first drive mechanism for driving an injection body of an injection unit of the card case and a second drive mechanism for driving of injection head communicated with the fluid of the injection body to rise and fall, so that the injectionbody performs injection and suction operation on accommodating grooves in a circular base plate of the card case; the card case rotation drive unit is used for driving the circular base plate of the card case to rotate around the axis, and the injection head can perform injection and suction operation on multiple accommodating grooves in the circular base plate; the controller controls the workingstates of the card case holding unit, the card case locking unit, the liquid supply drive unit and the card case rotation drive unit. The gene sequencing library preparation device can realize automation of library preparation.

Description

technical field [0001] The disclosure belongs to the technical field of gene sequencing, and in particular relates to a gene sequencing library preparation device. Background technique [0002] After the 1950s, with the development of molecular genetics, people gradually realized that the essence of genes is DNA fragments that control biological traits and have genetic effects. On the one hand, genes can faithfully replicate themselves to ensure the basic characteristics of organisms; on the other hand, genes can also mutate, leading to diseases. Gene sequencing can quickly and accurately obtain biological genetic information, reveal the complexity and diversity of the genome, and play a very important role in life science research; similarly, gene sequencing is also of great significance and value to clinical medicine. Mechanism research and clinical diagnosis gradually rely on gene sequencing technology. [0003] The traditional first-generation sequencing technology has...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C40B60/14
CPCC12Q1/6806C40B60/14
Inventor 谢世飞陈才夫华锦彪周建涛何开伟熊磊
Owner 3D BIOMEDICINE SCI & TECH CO LTD
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