Application of kandelia candel extract in petroleum ether in resistance of prostatic cancer

A technology of petroleum ether extraction and anti-prostate cancer, which can be used in medical preparations containing active ingredients, anti-tumor drugs, drug combinations, etc., and can solve problems such as difficulty in control

Inactive Publication Date: 2019-08-02
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the increase of aging population in China, the population of prostate cancer will continue to increase. If

Method used

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  • Application of kandelia candel extract in petroleum ether in resistance of prostatic cancer
  • Application of kandelia candel extract in petroleum ether in resistance of prostatic cancer
  • Application of kandelia candel extract in petroleum ether in resistance of prostatic cancer

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Experimental program
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Effect test

Embodiment 1

[0018] 1. Cell lines and culture conditions

[0019] Human prostate cancer cell lines DU145 and PC3 were purchased from the Chinese Academy of Sciences, respectively, with complete medium consisting of 10% FBS and 90% MEM, 10% FBS and 90% F12, at 37°C in 5% CO 2 cultured in an incubator.

[0020] 2. Experimental group

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Abstract

The invention discloses that a kandelia candel extract in petroleum ether has a good inhibitory effect on the proliferation of prostatic cancer cells. Accordingly, the inventor also establishes the corresponding preparation method of the extract. The experiments show that the kandelia candel extract in petroleum ether has resistance effect on prostatic cancer. It can be seen that kandelia candel has the potential value of anti-prostatic cancer drugs. Therefore, the invention provides a strong basis and reliable guarantee for further opening up the medical application of mangrove plant kandeliacandel, and also opens up a Chinese herbal medicine approach for the treatment of prostatic cancer.

Description

technical field [0001] The invention belongs to the technical field of prostate cancer treatment, and in particular relates to the anti-prostate cancer application of a candelabra petroleum ether extract. Background technique [0002] Kandelia candel (Linn.) Druce is a plant of the genus Kandelia Wight et Arn. in the family Rhizophoraceae, and is widely distributed in Guangdong, Guangxi, Fujian and Taiwan. According to the records of "Chinese Ocean Materia Medica", "candel, bitter and astringent; flat in nature; returns to liver and stomach meridian". Candela is one of the marine traditional Chinese medicines used by the Jing nationality, and the local name is Bilan. In Jing medicine, candela root can be used to treat rheumatoid arthritis; candela leaves can lower blood pressure; candela fruit can prevent cardiovascular diseases; its bark can treat traumatic bleeding, water and fire burns. Modern pharmacological studies have shown that candelabra extract has antibacterial,...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P13/08A61P35/00
CPCA61K36/185A61K2236/333A61K2236/35A61K2236/39A61P13/08A61P35/00
Inventor 郝二伟韦林垚侯小涛谢金玲邓家刚杜正彩
Owner GUANGXI UNIV OF CHINESE MEDICINE
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