Preparation and separation and purification method of an immunomodulatory peptide

Abstract

The invention provides a method for separating and purifying to obtain immunomodulatory peptides from Radix Radix, the method uses Radix Radix Astragali as a raw material, through protein extraction, double-step enzymolysis of pepsin and trypsin, separation and purification to obtain specific immune polypeptides, Its molecular weight is 949 Da, and its full amino acid sequence is: Tyr‑Gly‑Pro‑Ser‑Ser‑Tyr‑Gly‑Tyr‑Gly. The invention overcomes the shortcomings of the existing immunomodulatory drugs and eliminates the public's worries about artificial immunomodulators.

Description

technical field

[0001] The invention relates to a method for separating and purifying immunoregulatory peptides from Radix Pseudostellariae, belonging to the field of biotechnology. Background technique

[0002] Immunity is a specific physiological reaction that occurs when the body contacts "antigenic foreign bodies" or "foreign molecules", and its main purpose is to maintain the homeostasis of the body. The immune system is a network of cells, tissues, and organs that works to eliminate potentially harmful substances such as bacteria, viruses, fungi, protozoa, and to stop the growth of cancer cells. In the body's survival, the immune system acts as the first line of defense against pathogens, providing protection before bodily functions are impaired. However, the immune system is also affected by many factors, including stress, unhealthy lifestyle, pathogens and antigens, which can damage the body's immune system. As a result, drugs used to regulate the human immune resp...

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