Measuring and processing method and measuring device for rat intracavernous pressure data
The technology of a corpus cavernosum and a processing method is applied in the field of a method and a measuring device for measuring the pressure data in the corpus cavernosum of a rat, and can solve the problems of a large number of manpower and material resources, being unsuitable for simultaneous detection of a large number of experimental animals, and taking a long time to detect.
Inactive Publication Date: 2020-01-31
ZHEJIANG CHINESE MEDICAL UNIVERSITY
View PDF10 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0011] (1) The data analyzed and detected by the detection method in the prior art is not direct data, but belongs to indirect data, and the accuracy is poor
[0012] (2) The installation of implanted equipment has high requirements for surgical sterility, which requires a lot of manpower and material resources and expensive equipment
[0013] (3) The existing technology takes a long time to detect, and the unit price of the detection equipment is high, which is not suitable for the simultaneous detection of large quantities of experimental animals
[0014] (4) Existing technology detection equipment also needs to bury electrodes in advance, which is more labor-intensive and time-consuming in large-scale animal experiments
[0015] (5) Existing technology is not applicable to all experimental animals
[0016] (6) The existing apomorphine technology cannot directly compare the degree of erection and the use of drugs to induce erection has other potential unknown effects
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0057] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0058] The accuracy of the data analyzed and detected by the detection equipment in the prior art is poor. The installation of implanted equipment has high requirements for surgical sterility, requires a lot of manpower and material resources, and the equipment is expensive. The detection takes a long time and the unit price of the detection equipment is high, which is not suitable for the simultaneous detection of a large number of experimental animals. The existing detection equipment also needs to bury electrodes in advance, which is relatively labor-intensive and time-consuming in large-scale animal experiments.
[00...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention belongs to the technical field of medical science, and discloses a measuring and processing method and a measuring device for rat intracavernous pressure (ICP) data. The measuring and processing method includes the following steps: carrying out electrical stimulation on cavernous nerves for 1 minute and recording ICP; mean arterial pressure (MAP) measurement: inserting a PE-50 tube and connecting the PE-50 tube to a pressure transducer to record data; data processing: collect the ICP / MAP and the area under the curve (AUC). According to the ICP measuring technology disclosed by the invention, a 10 ml syringe needle or a 25-G intravenous injection needle connected to the PE-50 tube is used to be punctured into cavernous strips of the penis in rats after anaesthesia to separatethe cavernous nerves in the dorsal prostates of rats, the penis cavernous body erection is induced by the electrical stimulation on the cavernous nerves, and changes in ICP values are processed and recorded via a energy conversion device. Therefore, the ICP measuring technology has the advantages of directness, high efficiency, simple structure, etc., and the ICP measuring device has the advantages of cheapness, less subjectivity of experimental results, repeatability of experimental results, etc.
Description
technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a method for measuring and processing rat penile corpus cavernosum pressure data and a measuring device. Background technique [0002] Currently, the closest prior art: [0003] Erectile dysfunction (erectile dysfunction, ED) is one of the common sexual dysfunction diseases in men, which refers to the difficulty in achieving or maintaining a sufficient erection for male patients to achieve satisfactory sexual performance. Sexual life will affect the harmony of the family and cause unavoidable damage to the body and mind. [0004] Penile erection is subject to complex neurovascular regulation and is a neurovascular event. The penis is innervated by both autonomic and somatic nerves. The sympathetic and parasympathetic nerves converge in the pelvis to form cavernous nerves, enter the penile urethral cavernous body and glans, and regulate blood flow in the cavernous ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & AuthorityApplications(China)
IPC IPC(8): A61B5/00A61B5/0215A61B5/03
CPCA61B5/0215A61B5/031A61B5/4393A61B2503/40A61B2503/42
Inventor吕伯东马轲叶妙勇赵凡周康
OwnerZHEJIANG CHINESE MEDICAL UNIVERSITY