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A kind of animal external use parasite control agent and preparation method

A parasite and control agent technology, which is applied in the field of parasite control agent for external use in animals and its preparation, can solve the problems of ineffective insect eggs, unclean insect repellent, high price, etc., and achieve good insecticidal effect and low-dose insecticidal Active, quick effect

Active Publication Date: 2021-09-03
无锡派维药业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This product is more convenient to use, but the price is expensive, the effect is slow and the drug has little effect on the eggs, and the phenomenon of "relapse" is prone to occur a few days after use
In addition, the existing market reports that existing drugs such as Fulaien are generally not clean in repelling insects, especially ticks and mites. Mild to the skin, an external parasite control agent for animals that can repel termites

Method used

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  • A kind of animal external use parasite control agent and preparation method

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preparation example Construction

[0037] The present invention also provides a preparation method of the above-mentioned external parasite control agent for animals, comprising the following steps:

[0038] (1), the following components are provided by weight percentage: 5-15% of fiprenil; 1-5% of bifenthrin; 1.5-4% of pyriproxyfen; 1.5-5% of dinotefuran; 4-10%; antioxidant 0.01-0.5%; main solvent 25-35%; co-solvent amount.

[0039] (2), using the main solvent to completely dissolve the fiprenil, the bifenthrin, the pyriproxyfen and the dinotefuran respectively.

[0040] (3) Using an appropriate amount of co-solvent to dissolve the antioxidant.

[0041] (4) Mix the dissolved fiprenil, the bifenthrin, the pyriproxyfen, the dinotefuran, the antioxidant and the crystallization inhibitor and stir thoroughly.

[0042] (5) Add the co-solvent to 100%, fully stir, and filter to obtain the parasite control agent for external use on animals.

[0043] The external parasite control agent for animals can be a spray or a...

Embodiment 1

[0046] The formulation and preparation method of animal external parasite control agent provided by the present invention are as follows (1L):

[0047] (1), the following components are provided by weight percentage: 10% of fiprenil, i.e. 100g; 3% of bifenthrin, i.e. 30g; 1.8% of pyriproxyfen, i.e. 18g; 2% of dinotefuran, i.e. 20g ; PEG-200 5%, that is 50ml; BHT0.1%, that is 1g; BHA0.2%, that is 2g; ethyl lactate 3.6%, that is 36ml; N-methylpyrrolidone 28%, that is 280ml; diethylene glycol Proper amount of ether.

[0048] (2), measure 200ml N-methylpyrrolidone to dissolve all of the described fiprenil, fully stir until completely dissolved, and become a pale yellow solution; measure 60ml of N-methylpyrrolidone to dissolve all of the described flumethrin, Stir fully until bifenthrin is completely dissolved, and it is a colorless solution; measure 20ml of N-methylpyrrolidone to dissolve all of the dinotefuran, stir well, completely dissolve, and it is a colorless solution; use ...

Embodiment 2

[0053] The formulation and preparation method of animal external parasite control agent provided by the present invention are as follows (1L):

[0054] (1), the following components are provided by weight percentage: fiprenil 5%, i.e. 50g; bifenthrin 3%, i.e. 30g; pyriproxyfen 1.8%, i.e. 18g; dinotefuran 2%, i.e. 20g %; PEG-200 5%, that is 50ml; BHT0.1%, that is 1g; BHA0.2%, that is 2g; ethyl lactate 3.6%, that is 36ml; N-methylpyrrolidone 18.7%, that is 187ml; Proper amount of alcohol ether.

[0055] (2), take N-methylpyrrolidone to dissolve all of the fiprenil, the bifenthrin and the dinotefuran respectively, fully stir until completely dissolved; use all of the ethyl lactate to dissolve All of the pyriproxyfen was fully stirred and dissolved completely, and it was a colorless solution.

[0056] (3) Take an appropriate amount of diethylene glycol ether to completely dissolve all the BHT and BHA, and fully stir to form a colorless solution.

[0057] (4), the dissolved fipr...

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Abstract

The invention provides an external parasite control agent for animals and a preparation method thereof. The mass percentages of the components of the external parasite control agent for animals are as follows: 5-15% of fiprenil; 1-5% of bifenthrin; Pyriproxyfen 1.5-4%; dinotefuran 1.5-5%; crystallization inhibitor 4-10%; antioxidant 0.01-0.5%; main solvent 25-35%; co-solvent make up to 100%. The present invention uses fiprenil as the main active ingredient, and synergistically cooperates bifenthrin, pyriproxyfen and dinotefuran, so that it has a good deworming effect, and solves the poor deworming effect of the existing deworming drugs , for ticks, mites and other unclean problems, especially including fiprenil 10%, bifenthrin 3%, pyriproxyfen 1.8%, dinotefuran 2%, PEG‑200 5%, BHT0 .1%, BHA 0.2%, ethyl lactate 3.6%, N-methylpyrrolidone 28% and diethylene glycol ethyl ether appropriate amount of external parasite control agent for animals, the insecticidal effect is particularly good.

Description

technical field [0001] The invention relates to the technical field of parasite drugs, in particular to a parasite control agent for external use on animals and a preparation method thereof. Background technique [0002] At present, the pet market is developing rapidly, many families will feed cats, dogs and other pets, but cats, dogs and other pets are very vulnerable to the infestation and infection of parasites, such as fleas, mites, ticks, lice and other parasites, parasites will not only cause The uneasiness and disease of cute pets, and parasites are also the intermediate hosts of pathogens, which may bring a variety of zoonotic diseases to humans through pathogen infection and transmission media. There are many insecticides used to treat parasites in the field, and the effectiveness of these insecticides against particular parasites varies as well as their cost, such as fipronil, also known as fipronil, a French Rhone-Planck The pyrazole compound with insecticidal, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/415A61K31/4402A61K31/341A61K31/277A61K9/00A61K47/10A61K47/14A61K47/22A61P33/14
CPCA61K9/0017A61K31/277A61K31/341A61K31/415A61K31/4402A61K47/10A61K47/14A61K47/22A61P33/14A61K2300/00
Inventor 皮灿辉肖小平汪猜
Owner 无锡派维药业科技有限公司
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