Gold nanorod synthesis method for cancer photothermal therapy

Abstract

The invention discloses a gold nanorod synthesis method for cancer photothermal therapy. The method comprises the following steps: preparing a NaBH4 solution, and inserting the NaBH4 solution into icefor at least 10 minutes; meanwhile, adding a CTAB solution into a small glass bottle, putting the small glass bottle into a water bath of 30 DEG C, and slowly stirring; then adding an HAuCl4 solutioninto the CTAB solution, and then adding the NaBH4 solution which is inserted into the ice for more than 10 minutes under violent stirring to obtain a dark brown seed solution; then, slowly stirring at 30 DEG C, adding an AgNO3 aqueous solution, an HAuC4 solution, an ascorbic acid solution and a seed solution which stands for 1 hour in a water bath into the CTAB solution, continuously stirring for1 minute, then standing for 1 hour in the dark, transferring the solution into an Eppendorf tube, and centrifuging to remove supernatant, so as to obtain a solution precipitate; and finally, re-suspending the solution precipitate in phosphate buffer saline water to obtain the gold nanorod.

Description

technical field [0001] The invention relates to the technical field of nanomaterials, in particular to a method for synthesizing gold nanorods for photothermal therapy of cancer. Background technique [0002] Cancer is a major public health problem worldwide. According to statistics, in 2000, about 10 million people in the world suffered from malignant diseases, and more than 6 million people died of this cancer at the same time. Cancer is due to mutations in DNA in normal cells, and in contrast to healthy cells, abnormal DNA in cancer cells cannot be repaired. Also, the growth of cancer cells is uncontrolled. [0003] To treat cancer, many diagnostic and therapeutic methods have been developed since the 1970s. At present, most of the techniques widely used are invasive treatments, which are likely to cause systemic toxicity. Among them, the most effective treatment method is to perform surgery to remove the cancer site, but this method is not suitable for the treatment ...

AI Technical Summary

Problems solved by technology

However, because there are many conditions that affect the reaction results, comprehensive adjustments are usually required to achieve the expected results.

Images