Sample receiving device

a technology for receiving devices and samples, applied in the field of sample receiving devices, can solve the problems of increased cost of container manufacture, bulky/costly transportation, and inability to meet the needs of high-throughput analysis/testing or automation

Inactive Publication Date: 2015-06-04
DNA GENOTEK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention relates to a device for receiving and storing substances such as samples. The invention provides a sample receiving device comprising a lid with a reservoir for holding a substance and a pierceable membrane sealing the substance. A funnel is attached to the lid and has one or more cutting ribs for cutting the membrane without twisting it. The funnel has a tensioning means for maintaining tension on the membrane during cutting. The sample receiving device also has an expelling means for expelling a sample from a sample-containing absorbent device into the funnel. The invention also provides a kit comprising the sample receiving device, a sample receptacle, instructions for use, and, optionally, a cap for closing the sample receptacle and a biohazard bag for safe transport. The technical effects of the invention include efficient and safe storage of samples, with ease of use and removal of contaminants.

Problems solved by technology

A drawback of this container is that it includes multiple parts (e.g., lid, vial, disk, rod, rod holder), which increases the cost of manufacture of the container.
While the shape and size this container is well suited for collecting a biological sample from a donor, it does not lend itself well to high throughput analysis / testing or automation and is bulky / costly to transport.
Depending upon the nature of the substance released from the reservoir, the sponge may disintegrate and / or chemicals (e.g., adhesives) may be leached from the sponge and contaminate the sample.
Importantly, the presence of the sponge / applicator in the sample may interfere with down-stream analysis, e.g., processing using liquid-handling robots.
Liquid-handling robots may register an error upon contacting / colliding with a sponge in a sample; the robot may pierce through the sponge and successfully withdraw an aliquot, but inadvertently contaminate nearby samples as the pipette (with impaled sponge) passes over open tubes; there may be too little ‘free’ sample in the device for a robot or technician to recover for testing (i.e. the sponge soaks up and retains the sample-substance).

Method used

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Embodiment Construction

[0056]As will be discussed in more detail below, the present invention provides a sample receiving device designed to facilitate convenient sample collection and to maintain at least one substance, such as a preservative reagent, in a separate compartment for release into the sample following collection. The sample receiving device is further suitable for storing a concentrate / active ingredient separate from the substance stored in the lid, for example, as a dried mixture adhered to an inner surface of the lid, funnel and / or sample receptacle, such as a vial or tube, releasably or permanently attachable to the funnel.

[0057]The sample receiving device of the present invention has fewer component parts than are present in previously known sample receiving devices having a similar purpose. Thus, the device of the present invention can be less expensive and / or easier to manufacture and package, than such previous devices. Additionally, the manufacturing tolerances can be less precise fo...

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PUM

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Abstract

The present invention generally relates to a sample receiving device for releasably storing a substance. The sample receiving device includes a lid having a reservoir for retaining the substance, and a pierceable barrier sealing the substance within the reservoir; and b) a funnel for receiving a sample and configured for closure by the lid. The funnel is configured for releasable attachment to a sample receptacle such that a sample can be provided to the funnel and travel through the channel in the funnel into the sample receptacle. Further, the funnel includes one or more cutting ribs for cutting the pierceable barrier such that upon cutting of the pierceable barrier the substance is released from the reservoir, flows through the channel in the funnel and into the sample receptacle to be mixed with the sample. The present invention also provides a kit for collecting and storing biomolecules.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application is a continuation of U.S. application Ser. No. 12 / 737,821 filed May 10, 2011, now allowed, which is the 35 U.S.C. §371 national stage of PCT / CA2009 / 001153 filed Aug. 21, 2009, which claims the benefit and priority to U.S. provisional patent application No. 61 / 090,822, filed Aug. 21, 2008, the disclosures of all of which are incorporated herein in their entirety as though set forth explicitly herein.FIELD OF THE INVENTION[0002]The field of the invention generally relates to a sample receiving device. More particularly, the invention relates to a sample receiving device that releasably stores a reagent.BACKGROUND[0003]It is often desirable to store a substance, such as a liquid, solid, gas or mixtures thereof, in a container prior to mixing with another substance(s). For example, it can be desirable to package and store a composition, or compositions, in a container for shipping and / or safe storage and handling, prior to com...

Claims

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Application Information

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Patent Type & AuthorityApplications(United States)
IPC IPC(8): B01L3/00
CPCB01L3/50825B01L3/5029B01L2200/0689B01L2400/0683B01L2300/044B01L2300/0672B01L2200/141B01L2200/085B01L2200/16B01L2200/185B01L2300/021B01L2300/043B01L2300/047A61B10/0051A61B10/0096A61B2010/0006B01L1/52Y10T436/143333Y10T436/2525G01N1/00C12M1/26C12M3/00B01L9/54B01L2200/087B01L2200/12
InventorCURRY, IANSUNSTRUM, ROYJACKSON, ADELEMUIR, RODGRAHAM, ROMEOSIROIS, MIKE
OwnerDNA GENOTEK