Traditional Chinese medicine composition for treating diabetic nephropathy and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating diabetic nephropathy and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials: a garbanzo sprout extractive, astragalus membranaceus, codonopsis pilosula, carthamus tinctorius, ligusticum wallichii, radix achyranthis bidentatae, coptis chinensis, radix angelicae, radix ophiopogonis, radix rehmanniae preparata, cucumis satiuus and liquorice. According to the invention, the formula of the traditional Chinese medicine composition is reasonable, and the synergistic effect is good; a clinical verification result shows that a quite remarkable effect is achieved when the raw materials are matched to be used for treating the diabetic nephropathy.

Description

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating diabetic nephropathy and a preparation method thereof. Background technique

[0002] Diabetic nephropathy is one of the common complications of diabetes and one of the manifestations of systemic microvascular disease in diabetes. The clinical features are progressive renal damage, hypertension, edema, and severe renal failure in the late stage. It is one of the main causes of death in diabetic patients. one. In recent years, with the prolongation of the average life expectancy of the Chinese population, changes in living and eating habits, and structural changes, the prevalence of diabetes has shown a linear upward trend, and due to the improvement of treatment methods, the increase in survival time, diabetic nephropathy and other complications have also increased.

[0003] In Chinese medic...

Examples

Embodiment 1

[0035] The pharmaceutical composition of Example 1 of the present invention includes the following preparation raw materials in parts by weight: 5 parts of chickpea bean sprouts extract, 6 parts of Radix Astragali, 9 parts of Codonopsis pilosula, 3 parts of safflower, 3 parts of Rhizoma Chuanxiong, 3 parts of Achyranthes bidentata, 5 parts of Coptis chinensis 1 part of Angelica dahurica, 1 part of Ophiopogon japonicus, 9 parts of Rehmannia glutinosa, 3 parts of cucumber seeds and 1 part of licorice.

[0036] The preparation method is as follows:

[0037] 1) To prepare chickpea bean sprouts extract, germinate chickpeas for 4 days, pick bean sprouts, dry them, crush them into coarse powder, add 20 times the weight of coarse powder, and 70% ethanol aqueous solution, soak until thoroughly, Heat to 90°C, reflux and extract 3 times, each time for 1.5 hours, filter the extract to obtain the filtrate, depressurize the filtrate to recover ethanol until the alcohol concentration of the ...

Embodiment 2

[0041]The pharmaceutical composition of Example 2 of the present invention includes the following preparation raw materials in parts by weight: 30 parts of chickpea bean sprouts extract, 30 parts of Astragalus membranaceus, 30 parts of Codonopsis pilosula, 20 parts of safflower, 20 parts of Chuanxiong, 15 parts of Achyranthes bidentata, 20 parts of Coptis chinensis 20 parts of Angelica dahurica, 10 parts of Ophiopogon japonicus, 15 parts of Rehmannia glutinosa, 20 parts of cucumber seeds and 15 parts of licorice.

[0042] The preparation method is the same as in Example 1.

Embodiment 3

[0044] The pharmaceutical composition of Example 3 of the present invention includes the following preparation raw materials in parts by weight: 25 parts of chickpea bean sprouts extract, 20 parts of Radix Astragali, 20 parts of Codonopsis pilosula, 14 parts of safflower, 18 parts of Rhizoma Chuanxiong, 10 parts of Achyranthes bidentata, 14 parts of Coptis chinensis 10 parts of Angelica dahurica, 5 parts of Ophiopogon japonicus, 10 parts of Rehmannia glutinosa, 15 parts of cucumber seeds and 10 parts of licorice.

[0045] The preparation method is the same as in Example 1.

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating diabetic nephropathy and a preparation method thereof. Background technique

[0002] Diabetic nephropathy is one of the common complications of diabetes and one of the manifestations of systemic microvascular disease in diabetes. The clinical features are progressive renal damage, hypertension, edema, and severe renal failure in the late stage. It is one of the main causes of death in diabetic patients. one. In recent years, with the prolongation of the average life expectancy of the Chinese population, changes in living and eating habits, and structural changes, the prevalence of diabetes has shown a linear upward trend, and due to the improvement of treatment methods, the increase in survival time, diabetic nephropathy and other complications have also increased.

[0003] In Chinese medic...

Examples

Embodiment 1

[0035] The pharmaceutical composition of Example 1 of the present invention includes the following preparation raw materials in parts by weight: 5 parts of chickpea bean sprouts extract, 6 parts of Radix Astragali, 9 parts of Codonopsis pilosula, 3 parts of safflower, 3 parts of Rhizoma Chuanxiong, 3 parts of Achyranthes bidentata, 5 parts of Coptis chinensis 1 part of Angelica dahurica, 1 part of Ophiopogon japonicus, 9 parts of Rehmannia glutinosa, 3 parts of cucumber seeds and 1 part of licorice.

[0036] The preparation method is as follows:

[0037] 1) To prepare chickpea bean sprouts extract, germinate chickpeas for 4 days, pick bean sprouts, dry them, crush them into coarse powder, add 20 times the weight of coarse powder, and 70% ethanol aqueous solution, soak until thoroughly, Heat to 90°C, reflux and extract 3 times, each time for 1.5 hours, filter the extract to obtain the filtrate, depressurize the filtrate to recover ethanol until the alcohol concentration of the ...

Embodiment 2

[0041]The pharmaceutical composition of Example 2 of the present invention includes the following preparation raw materials in parts by weight: 30 parts of chickpea bean sprouts extract, 30 parts of Astragalus membranaceus, 30 parts of Codonopsis pilosula, 20 parts of safflower, 20 parts of Chuanxiong, 15 parts of Achyranthes bidentata, 20 parts of Coptis chinensis 20 parts of Angelica dahurica, 10 parts of Ophiopogon japonicus, 15 parts of Rehmannia glutinosa, 20 parts of cucumber seeds and 15 parts of licorice.

[0042] The preparation method is the same as in Example 1.

Embodiment 3

[0044] The pharmaceutical composition of Example 3 of the present invention includes the following preparation raw materials in parts by weight: 25 parts of chickpea bean sprouts extract, 20 parts of Radix Astragali, 20 parts of Codonopsis pilosula, 14 parts of safflower, 18 parts of Rhizoma Chuanxiong, 10 parts of Achyranthes bidentata, 14 parts of Coptis chinensis 10 parts of Angelica dahurica, 5 parts of Ophiopogon japonicus, 10 parts of Rehmannia glutinosa, 15 parts of cucumber seeds and 10 parts of licorice.

[0045] The preparation method is the same as in Example 1.

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