This utility model discloses a telescopic frame structure and a two-wheeled vehicle, including an upper frame body and a lower frame body arranged vertically and telescopically connected. The upper frame body includes an upper crossbeam for connecting to the front wheel of the handlebars, extending along a first direction. The lower frame body includes a lower crossbeam, a lower support member, and a locking
assembly for locking or releasing the upper and lower crossbeams. The lower crossbeam extends along the first direction. The upper and lower crossbeams are telescopically connected in a surface-fitting manner along the first direction. The upper end of the lower support member is connected to the lower crossbeam, and the lower end of the lower support member extends away from the upper crossbeam. This telescopic frame structure has good stability, is easy and quick to operate, and can be telescopically extended manually or electrically. It will not damage the vehicle's paint finish during the extension and retraction process due to friction and compression. Different types and sizes of vehicle models using this telescopic frame structure can achieve telescopic functionality. It is compact, easy to
package and transport, and reduces transportation costs.