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Medicinal composition for part use for treating acne and method for preparing the same

A technology for topical use and composition, which is applied in the fields of medicine and cosmetics, and can solve problems such as the abuse of antibiotics

Inactive Publication Date: 2008-01-30
大连奥森制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many anti-acne products on the market, and the abuse of antibiotics, glucocorticoids, and chemicals is very serious, and the results are worrying

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1: Preparation of the ointment of the medicine of the present invention

[0042] Prescription: stearic acid 120g, castor oil 100g, ethyl paraben 1g, liquid paraffin 100g, triethanolamine 9g, glycerin 40g, natural bezoar 2g, skullcap extract 4g, honeysuckle extract 4g, distilled water to 1000g

[0043] Preparation method: Put stearic acid, castor oil, and liquid paraffin in an evaporating dish, heat on a water bath (75-80°C) to melt, and then take triethanolamine, ethyl paraben, glycerin, and an appropriate amount of water, mix well, and heat to At the same temperature, slowly add to the oil phase, add and stir until the emulsification is complete, then add natural bezoar, skullcap extract, honeysuckle extract, add and stir, distilled water to 1000g, and then stir to room temperature.

Embodiment 2

[0044] Example 2: Preparation of the ointment of the medicine of the present invention

[0045] Prescription: 13g stearic acid, 17g glyceryl monostearate, 5g front wax, 75g ozokerite, 450g liquid paraffin, 70g white petrolatum, 10.0g aluminum distearate, 1.0g calcium hydroxide, 1.5g ethyl paraben , Artificial bezoar 1g, Scutellaria baicalensis extract 5g, honeysuckle extract 10g, distilled water added to 1000g.

[0046] Preparation method Take stearic acid, glyceryl monostearate, beeswax, and ceresin on a water bath to heat and melt, then add liquid paraffin, white petrolatum, aluminum distearate, heat to 85 ° C, and add calcium hydroxide, hydroxyl Phenylethyl ester is dissolved in distilled water, heated to 85°C, gradually added to the oil phase, stirring while adding, then artificial bezoar, skullcap extract, honeysuckle extract, distilled water to 1000g, homogenizer treatment uniformly, that is, it is obtained.

Embodiment 3

[0047] Example 3: Preparation of the ointment of the medicine of the present invention

[0048] Prescription: 220g of stearyl alcohol, 15g of sodium lauryl sulfate, 250g of white petrolatum, 0.25g of ethyl paraben, 0.75g of propyl paraben, 120g of glycerin, 5g of artificial bezoar, 10g of skullcap extract, 10g of honeysuckle extract in distilled water Add to 1000g

[0049] Preparation method: Melt stearyl alcohol and white vantolin on a water bath, heat to 80°C, add sodium lauryl sulfate, ethylparaben, propylparaben, glycerin pre-dissolved in water and heated to 80°C , artificial bezoar, scutellaria baicalensis extract, honeysuckle flower extract, stir until condensation, that is, get.

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PUM

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Abstract

The present invention relates to a locally applied pharmaceutical composition to treat acne, which contains bezoar, baical skullcap root extract, honeysuckle flower extract and substrate. The preparation method is to add the gel substrate which is commonly used in pharmacy and use the common method in pharmacy to prepare the gel; or to add the ointment sustrate which is commonly used in pharmacy and use the common method in pharmacy to prepare the ointment and so on. The present invention has the significant treatment effects on acne, but has no antibiotics, glucocorticoids, chemicals, and side effects.

Description

technical field [0001] The invention relates to a topical pharmaceutical composition for treating acne and a preparation method, in particular to a pharmaceutical composition and a preparation method using traditional Chinese medicine extracts as raw materials, and belongs to the technical field of medicines and cosmetics. Background technique [0002] Acne, commonly known as acne, is an inflammatory lesion that occurs in the hair follicles and sebaceous glands and its surrounding tissues. It is more common in all kinds of people, especially young people. To this end, many cosmetic companies have launched acne products. The type and content of active ingredients in acne-removing products not only determine the pros and cons of acne-removing effects, but also have a certain impact on the health of consumers. Antibiotics and glucocorticoids have a certain therapeutic effect on acne and are often used in external medicine. Salicylic acid has moderate anti-acne and antibacteri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K9/00A61K9/06A61K8/98A61P17/10A61Q19/06A61K35/413
Inventor 张为胜李诗标张晶刘元水高尚峰
Owner 大连奥森制药有限公司
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