Complex preparation of stephanotis and antibiotic for treating infectious disease

A technology for infectious diseases and compound preparations, applied in the field of compound preparations of Baiyaozi and antibiotics, can solve problems such as enhancing the sensitivity of drug-resistant bacteria, so as to solve the problem of bacterial drug resistance, enhance in vitro antibacterial activity, and enhance animal resistance in vivo. effect of infection

Inactive Publication Date: 2010-06-02
王教玉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

In this new type of medicine called Antimicrobium (antagonizing harmful microorganisms) it has several advantages that make them more effective against certain types of disease than older drugs like penicillins or cephalosporins. It also helps fight off resistances by killing these organism instead of fighting their own growth altogether.

Problems solved by technology

This patented technical solution described in this patents involves developing novel drugs that can control or even eliminate resistant microorganisms without causing their harmful effects when they are introduced into humans due to poor patient compliance issues associated with current therapy methods like chemotherapeusis.

Method used

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  • Complex preparation of stephanotis and antibiotic for treating infectious disease
  • Complex preparation of stephanotis and antibiotic for treating infectious disease
  • Complex preparation of stephanotis and antibiotic for treating infectious disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 100 g of Baiyaozi decoction pieces, powder it into a fine powder in a Soxhlet extractor, extract with 70% ethanol under reflux for 4 hours, recover ethanol, and obtain 0.7 g of Baiyaozi extract.

Embodiment 2

[0019] Under GMP conditions, take Baiyaozi extract and cephalexin respectively according to their content conversion, and prepare according to the tablet / capsule production standard with the ratio of Baiyaozi extract and cephalexin anhydrous as 8:1 (weight ratio) into Baiyaozi extract / cephalexin tablet or capsule.

Embodiment 3

[0021] Under GMP conditions, take Baiyaozi extract and oxacillin sodium respectively according to their content conversion, and use Baiyaozi extract and oxacillin sodium anhydrous as 8:1 (weight ratio) according to aseptic operation According to the technical specifications, mix evenly in the mixer, calculate the average loading, put it into sterilized glass bottles in the ultra-clean workbench (partial 100 grade), put on the plug, press the cap, and label to obtain the Baiyaozi compound / Antibiotic powder injection.

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Abstract

The invention relates to a traditional Chinese medicine which solves the problem of medicine resistance by being in compatibility with antibiotic i.e. a complex preparation of stephanotis and the antibiotic for treating infectious diseases. The complex preparation is prepared by mixing stephanotis extract and the antibiotic according to a specified proportion, and the complex preparation can inhibit medicine resistance, obviously strengthen in vitro antibacterial activity and animal in vivo anti-infection effect of the antibiotic, can obviously enlarge an antibacterial spectrum of the antibiotic, expand a clinical application range thereof, efficiently solve the problem of bacterial medicine resistance and strengthen the clinical effect thereof.

Description

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Claims

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Application Information

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Owner 王教玉
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