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Chinese medicine composition preparation for liver soothing and depression relief and quality control method

A quality control method, a technology for soothing the liver and relieving depression, which can be used in drug combinations, pharmaceutical formulations, medical raw materials for non-living substances, etc., and can solve problems such as low side effects

Active Publication Date: 2010-07-14
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, clinical treatment drugs for depression generally have side effects, while traditional Chinese medicine has the characteristics of low side effects in the treatment of diseases, so using Chinese medicine to treat depression has become a new treatment idea

Method used

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  • Chinese medicine composition preparation for liver soothing and depression relief and quality control method
  • Chinese medicine composition preparation for liver soothing and depression relief and quality control method
  • Chinese medicine composition preparation for liver soothing and depression relief and quality control method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0257] Bupleurum 40g, Jujube 30g, Shichangpu 40g, Pinellia (made) 30g, Atractylodes macrocephala (stir-fried) 30g, Floating wheat 100g, Polygala (made) 40g, Licorice (burned) 30g, Gardenia (stir-fried) 40g, Lily 100g , Dannanxing 40g, Curcuma 40g, Dragon Teeth 100g, Suanzaoren (fried) 50g, Poria cocos, 50g, Angelica 30g

[0258] The above sixteen flavors were decocted three times with water, the first time for 3 hours, the second and third times for 2 hours each, combined the decoction, filtered, the filtrate was concentrated to dryness, crushed, and made into granules. Dried, made into 100 bags, that is.

Embodiment 2

[0260] Bupleurum 50g, Jujube 30g, Shichangpu 50g, Pinellia (made) 30g, Atractylodes macrocephala (stir-fried) 40g, floating wheat 100g, polygala (made) 40g, licorice (broiled) 30g, gardenia (stir-fried) 40g, lily 100g , Dannanxing 40g, Curcuma 40g, Dragon Tooth 90g, Suanzaoren (fried) 40g, Poria 40g, Angelica 40g

[0261] The above sixteen flavors are decocted three times with water, the first time is 3 hours, the second and third time are 2 hours respectively, the decoctions are combined, filtered, the filtrate is concentrated to dryness, crushed, and made into capsules.

Embodiment 3

[0262] Embodiment 3 quality control method

[0263] Identification: (the following products are the granules prepared in Example 1)

[0264](1) Take 20g of this product and add 40ml of water to dissolve it, put it in a separatory funnel, shake gently with petroleum ether (60-90°C) and extract 4 times (40ml, 40ml, 30ml, 30ml) to combine the ether layer, and concentrate it in a water bath to about 1ml , as the test solution. Add 1 g of Atractylodes macrocephala reference medicinal material and add 40 ml of water to decoct for 30 minutes, let it cool, and gently shake the supernatant with petroleum ether (60-90 ° C) to extract twice, 30 ml each time, combine the ether layer, concentrate in a water bath to about 1 ml, As Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome 30μl each of the above two solutions is taken and spo...

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Abstract

The invention discloses a Chinese medicine composition preparation for liver soothing and depression relief and a quality control method. The composition is prepared with such raw materials as bupleurum roots, Chinese dates, grassleaved sweetflag rhizome, pinellia tuber, bighead atractylodes rhizome, light wheat, polygala roots, licorice, gardenia, lily and the like. The composition preparation has good effect on depression prevention. The content determination method of the invention has good testing specificity, high stability, good reproducibility and high precision, is more suitable for industrial production and really guarantees the safety, effectiveness and reliability of clinical application.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition preparation and a quality control method, in particular to a traditional Chinese medicine composition preparation and a quality control method for soothing the liver and relieving stagnation, calming the nerves and calming the mind. Background technique [0002] Depression is characterized by upset, anxiety, insomnia, and forgetfulness. Depression seriously plagues the life and work of patients, and brings a heavy burden to families and society. A joint study by the World Health Organization, the World Bank and Harvard University shows that depression has become the second largest disease burden in China. [0003] At present, clinical treatment drugs for depression generally have side effects, while traditional Chinese medicine has the characteristics of low side effects in the treatment of diseases, so using Chinese medicine to treat depression has become a new treatment idea. The c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/24G01N30/02G01N30/90A61K35/02
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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