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Method for preparing nanometer traditional Chinese medicine for treating severe asthma and production method thereof

A technology of nano-Chinese medicine and its production method, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, and drug combinations. strong effect

Inactive Publication Date: 2011-06-22
SUZHOU ZHIWEITANG BIOLOGICAL TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0021] Looking further, the present invention uses the theory of yang greater than yin to develop a nano-Chinese medicine for the treatment of severe asthma. According to the conclusion of the novelty search report, there is no literature report on the development of nano-Chinese medicine products using the theory of yang greater than yin at present.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Prepare the following APIs according to the aforementioned method:

[0060] Extracts, nanoparticles, microcapsules, nanoparticles.

[0061] The composition of the raw materials made into the effective ingredients according to the weight ratio is ——

[0062] 15 parts of scutellaria, 15 parts of schisandra, 20 parts of psoralen, 8 parts of Tripterygium, 15 parts of Peucedanum, 10 parts of Cassia twig, 40 parts of Astragalus, 20 parts of Dilong, 8 parts of Pinellia, 6 parts of Licorice, Yunling 15 parts, Angelica 20 parts, Suzi 15 parts, Gecko 1 part, Xinyi 15 parts, Shegan 20 parts, Selenium-enriched tea 10 parts, Atractylodes 25 parts, Morinda officinalis 20 parts, Roasted ephedra 8 parts, Houttuynia cordata 20 parts .

[0063] The manufacturing process is as follows:

[0064] After mixing the extract, nanoparticles, microcapsules, and nanoparticles in a GMP10000 clean room at a ratio of 4:2:2:2, the latest version of the "Chinese Pharmacopoeia" preparation part of the hard caps...

Embodiment 2

[0066] Prepare the following APIs according to the aforementioned method:

[0067] Decoction concentrates, nano liposomes, nano emulsions, micro emulsions, nano suspensions.

[0068] The raw material composition of the active ingredients is as follows: 15 parts of scutellaria, 15 parts of schisandra, 20 parts of psoralen, 8 parts of tripterygium, 15 parts of Peucedanum, 10 parts of cinnamon sticks, 40 parts of astragalus 20 parts of dragon, 8 parts of pinellia, 6 parts of licorice, 15 parts of Yunling, 20 parts of Angelica sinensis, 15 parts of Suzi, 1 part of gecko, 15 parts of Xinyi, 20 parts of Shegan, 10 parts of selenium-enriched tea, 25 parts of Baizhu 20 parts of Jitian, 8 parts of Roasted Ephedra, 20 parts of Houttuynia cordata.

[0069] The manufacturing process is as follows:

[0070] After mixing the decoction concentrate, nano-liposomes, nano-emulsion, micro-emulsion, and nano-suspension in a GMP10000 clean room at a ratio of 5:1:1:1:2:1, use the latest version of "Chines...

Embodiment 3

[0072] Prepare the following APIs according to the aforementioned method:

[0073] Extracts, solid lipid nanoparticles, nanoemulsions.

[0074] The raw material composition of the active ingredients is as follows: 15 parts of scutellaria, 15 parts of schisandra, 20 parts of psoralen, 8 parts of tripterygium, 15 parts of Peucedanum, 10 parts of cinnamon sticks, 40 parts of astragalus 20 parts of dragon, 8 parts of pinellia, 6 parts of licorice, 15 parts of Yunling, 20 parts of Angelica sinensis, 15 parts of Suzi, 1 part of gecko, 15 parts of Xinyi, 20 parts of Shegan, 10 parts of selenium-enriched tea, 25 parts of Baizhu 20 parts of Jitian, 8 parts of Roasted Ephedra, 20 parts of Houttuynia cordata.

[0075] The manufacturing process is as follows:

[0076] After mixing the extract, solid lipid nanoparticles, and nanoemulsion in a 4:3:3 ratio in a GMP10000 clean room, the latest version of the "Chinese Pharmacopoeia" preparation partial film standard is adopted, and the film forming m...

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Abstract

The invention relates to a method for preparing a nanometer traditional Chinese medicine for treating severe asthma and a production method thereof. The nanometer traditional Chinese medicine comprises the following raw materials in part by weight: 10 to 20 parts of radish seed, 10 to 20 parts of shizandra berry, 15 to 30 parts of malaytea scurfpea, 6 to 12 parts of common threewingnut root and the like. The production process comprises the following steps of: ultrasonic extracting, microwave extracting, supersonic crushing, nanometer grinding, mixing, filling and the like. In the method, the nanometer traditional Chinese medicine has the synergetic and multi-targeting effects of nanometer medicaments. Products have the effects of concurrent treatment of lung, spleen, kidney and liver, tonification and purgation in combination and the like by treatment methods of warming yang, keeping strong and healthy, replenishing qi to invigorate spleen, warming lung to eliminate cold, resolving sputum, relieving asthma, dispelling dampness, resolving sputum, tonifying kidney, holding qi and the like. The nanometer traditional Chinese medicine has good effect of treating the severe asthma, can enhance the immunity in human bodies and does not have toxic or side effects.

Description

Technical field [0001] The invention relates to a nano traditional Chinese medicine for treating severe asthma. The invention also relates to a preparation and production method of the medicine. Background technique [0002] About 1.5 billion people in the world suffer from asthma, and China has 10 to 20 million patients, most of whom are young adults and children. It has become a major chronic disease that seriously endangers people's health. Its prevention and treatment have become a hot spot for authors in clinical Chinese and Western medicine. [0003] Western medical pathology confirmed that there was infiltration of eosinophils and lymphocytes in the early bronchial mucosa. There is mild hypertrophy of the bronchial smooth muscle. As the disease progresses, there may be changes in bronchial and bronchial mucus secretion, thickening and degeneration of basement membrane, and damage and shedding of ciliated epithelial cells. Obstructive emphysema may be complicated in the l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61K9/00A61P11/06A61K35/56A61K35/64A61K35/583A61K35/62
Inventor 杨洪舒
Owner SUZHOU ZHIWEITANG BIOLOGICAL TECH
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