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Medicinal composition for treating urinary system diseases

A technology of urinary system and composition, applied in the fields of urinary system diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as bladder inflammation, burden, increase bacterial resistance, etc., and achieve slow inflammation, high structure and specific surface area value, The effect of good biocompatibility

Active Publication Date: 2013-05-29
FENG CHIA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] However, after treatment with the above-mentioned drugs, although a large number of bacteria will be killed, it will also lead to the production of toxoids (Lipopolysaccharides, LPS), that is, ester polysaccharides. Clinically, toxoids (LPS) are derived from bacterial cell walls and can cause Bladder inflammation, while inducing bladder cells to secrete cytokines (cytokine), including IL-1α, β, TNF-α, IL-6, IL-8 and IL-10 and other inflammatory factors, inflammatory factors and play a key role, promote The accumulation of white blood cells in the bladder causes redness, swelling, heat, pain and inflammation, and severe cases cause bleeding. The above phenomenon is also common in people who have been carrying a urinary catheter for a long time. Because exogenous bacterial infection cannot be avoided, it will cause complicated infection problems. Such as chronic bladder inflammation, etc., and some patients may die of severe bacterial infection or even sepsis due to incomplete treatment. remission within a short period of time, or long-term treatment with the use of this preventive technique, and some side effects during treatment
[0005] However, for the treatment of cystitis, if we only rely on antibacterial drugs to treat the infection, the expected effect is often not achieved, and patients often seek medical treatment after bacterial infection and a large number of reproduction, because of redness, swelling, heat, and pain. Delaying the treatment time will also cause a greater burden on the body and increase the risk of bacterial resistance, which is also the main reason why complicated bacterial infection or drug-resistant bacterial infection cystitis is difficult to treat, and the bladder mucosa and interstitial tissue cannot be treated immediately. Repair to prevent more bacteria from entering; if the bacteria that cause bladder inflammation can be quickly absorbed when the bladder is inflamed, and the impact of endotoxins on the human body can be removed, the damaged bladder mucosa and interstitial tissue can be repaired to prevent bacteria from entering and multiplying, and promote Only when the wound on the surface of the bladder is healed can the infection be more effectively controlled to prevent recurrent attacks and relieve the symptoms of cystitis patients, which is really necessary

Method used

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  • Medicinal composition for treating urinary system diseases
  • Medicinal composition for treating urinary system diseases
  • Medicinal composition for treating urinary system diseases

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Embodiment Construction

[0038] A preferred embodiment of the pharmaceutical composition for treating the urinary system of the present invention, the pharmaceutical composition for treating the urinary system mainly contains a carbon material with a carbon content of more than 60 wt% on an aqueous carrier, so that the two or form a pharmaceutically acceptable aqueous carrier loaded with a carbon material selected from carbon fibers, activated carbon fibers, activated carbon, graphite, expanded graphite, carbon nanotubes, nanocarbon spheres, coke spheres or carbon black A carbon material of one of them or a group thereof, and the diameter of the carbon material is between 20nm and 2mm, the carbon layer plane stack thickness (Lc) is between 1nm and 1000mm, and the structure and specific surface area value (BET) is 20m 2 / g-4000m 2 Between / g, wherein, its carbon material of preferred embodiment of the present invention is activated carbon fiber powder or activated carbon, and the weight percentage of ...

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Abstract

The invention provides a medicinal composition for treating urinary system diseases. A carbon material of which the carbon content is over 60 percent by weight is loaded onto a water-containing carrier to form a pharmaceutically-acceptable water-containing carrier loaded with the carbon material; the unit dosage of the carbon material is between 0.1 mg / ml and 500 mg / ml; the diameter of the carbonmaterial is between 2 nanometers and 2 millimeters; and the carbon material can be combined with metal particles such as silver, platinum, palladium, gold, zinc or copper and the like. The medicinal composition can be contacted with a bladder in an animal body and relevant tissues, has the effects of sterilizing and lowering cystitis, effectively controlling infection, prompting healing of a wound on the surface of the bladder, and relieving the symptoms of a patient suffering from cystitis.

Description

technical field [0001] The present invention is related to the pharmaceutical composition, which is further a pharmaceutical composition for treating the urinary system by loading the carbon material on an aqueous carrier to form a pharmaceutically acceptable aqueous carrier loaded with the carbon material. Background technique [0002] Press, the well-known common urinary system diseases are mostly cystitis or urinary tract infection, the urinary system may be caused by bacteria, chemical drugs, radiation, anticancer drugs or exogenous bacterial infection, or it may be caused by the administration of drugs It is caused by bacterial invasion due to decreased resistance, and it is especially common in women or patients who use urinary catheters. The simplest way to judge whether cystitis occurs is to determine whether bacteriuria occurs or not, that is, per milliliter of urine The amount of bacteria in the urine is greater than 105 CFU, among which, about 98% of males have ba...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/04A61K47/02A61P13/10
Inventor 柯泽豪程千里洪铭谦袁小云张世毅
Owner FENG CHIA UNIVERSITY
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