Application of friedelin-3 beta-alcohol to preparation of vascular dementia-resisting medicaments

An untethered, anti-vascular technology, which is applied in drug combinations, cardiovascular system diseases, and pharmaceutical formulations, can solve problems such as the difficulty of curing vascular dementia, and achieve excellent therapeutic effects, inhibition of changes, and broad market prospects.

Inactive Publication Date: 2012-04-04
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] At present, it is still difficult to cure vascular dementi

Method used

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  • Application of friedelin-3 beta-alcohol to preparation of vascular dementia-resisting medicaments
  • Application of friedelin-3 beta-alcohol to preparation of vascular dementia-resisting medicaments
  • Application of friedelin-3 beta-alcohol to preparation of vascular dementia-resisting medicaments

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Abstract

The invention provides application of a natural product, namely friedelin-3 beta-alcohol, to the preparation of vascular dementia-resisting medicaments. Tested by experiments on living animals, the friedelin-3 beta-alcohol can effectively inhibit histomorphology change of nerves of a rat with vascular dementia, improve the cognition, learning and memorizing ability of the rat with the vascular dementia, and obviously relieve vascular dementia symptoms.

Description

technical field [0001] The present invention relates to the application of terpene-3β-alcohol, in particular to the application of terpene-3β-alcohol in the preparation of anti-vascular dementia medicine. Background technique [0002] Vascular dementia (VD) refers to the acquired intelligence impairment syndrome caused by brain dysfunction caused by various cerebrovascular diseases. A group of psychotic syndromes mainly characterized by impairment of memory and cognitive functions, accompanied by speech, movement, visuospatial and personality disorders as the main clinical manifestations. Vascular dementia is a frequently-occurring and common disease among middle-aged and elderly people, and it is one of the main types of senile dementia. Statistics show that in European and American countries, vascular dementia accounts for 15% of the total number of senile dementias; in China, Japan and other Asian countries, vascular dementia accounts for 50% of the total number of senil...

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Application Information

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IPC IPC(8): A61K31/56A61P25/28A61P9/00A61P25/14A61P25/18
Inventor 李鹏李建华王国红白瑞樱段树鹏朱利红张群妹高建辉尹雅玲孙瑞利王倩倩杨静赵蕴杨丽霞陈丽李嘉
Owner XINXIANG MEDICAL UNIV
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