Trace magnetic particle sampler

A magnetic particle and sampler technology, which is applied to the sampling device and other directions, can solve the problems of complicated operation and loss, and achieve the effects of fast and convenient operation, small volume, fast, convenient and accurate pipetting.

Inactive Publication Date: 2012-06-13
BEIJING JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The filtration method mainly uses a sand funnel, and filter paper is used, which will cause some magnetic particles to stand on the paper and lose part; while the magnet adsorption method does not use paper, but the operation is cumbersome

Method used

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  • Trace magnetic particle sampler
  • Trace magnetic particle sampler

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Experimental program
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Effect test

Embodiment 1

[0024] Using the micro magnetic particle sampler described in this embodiment to take micro Fe3O4 magnetic particles, the specific steps are:

[0025] (1) The dispersion system of Fe3O4 magnetic particles is configured with a concentration of 2%, wherein the diameter of the Fe3O4 magnetic particles is about 1um;

[0026] (2) Press the pressing cap 1 above, and the neodymium iron stilbene permanent magnet block 6 enters the magnetically conductive stainless steel jacket 7;

[0027] (3) Extending it into the prepared Fe3O4 colloidal magnetic particle dispersion system can realize the adsorption of magnetic particles;

[0028] (4) Take it out from the dispersion system and extend it into another container. By pressing the pressing cap 1 above again, the permanent magnet block 6 can be retracted into the magnetically conductive stainless steel casing 3, thereby leaving the outer casing and the magnetic particles entering In the designated container, the sampling of magnetic parti...

Embodiment 2

[0030] Using the micro magnetic particle sampler described in this embodiment to take micro ZrO2 / Fe3O4 magnetic particles, the specific steps are:

[0031] (1) Configure a ZrO2 / Fe3O4 magnetic particle dispersion system with a concentration of 1%, wherein the diameter of the ZrO2 / Fe3O4 magnetic particles is about 0.2um;

[0032] (2) Press the pressing cap 1 above, and the rubber permanent magnet block 6 enters the magnetically conductive stainless steel jacket 7;

[0033] (3) Extending it into the configured ZrO2 / Fe3O4 colloidal magnetic particle dispersion system can realize the adsorption of magnetic particles;

[0034] (4) Take it out from the dispersion system and extend it into another container. By pressing the pressing cap 1 above again, the permanent magnet block 6 can be retracted into the magnetically conductive stainless steel casing 3, thereby leaving the outer casing and the magnetic particles entering In the designated container, the sampling of magnetic particle...

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Abstract

The invention discloses a trace magnetic particle sampler, comprising a pressing cap (1), a ratchet wheel structure (2), a shell (3), a column core (4), a spring (5), a permanent magnet block (6) and an outer sleeve (7). The trace magnetic particle sampler is characterized in that: the pressing cap (1) is installed on the ratchet wheel structure (2) and is clamped in the shell (3); the column core (4) is tightly installed below the ratchet wheel structure (2) and the spring (5) is clamped on the column core (4) and the shell (3); the permanent magnet block (6) is tightly connected with the column core (4) through a groove type structure and the outer sleeve (7) is tightly connected below the shell (3). The trace magnetic particle sampler has the beneficial effects that: the trace magnetic particle sampler has the advantages of small volume, fastness and convenience for operation and the like; and some defects in an existing operation method are better improved, so that the realization of rapidly and conveniently obtaining trace magnetic particles is simple, convenient and fast.

Description

technical field [0001] The invention belongs to a micro-magnetic particle pipetting device, and is especially applied to a laboratory micro-magnetic particle sampler. Background technique [0002] Magnetic particles have many unique properties, so they are widely used in chemical, metallurgical, biotechnology and biomedical fields, such as magnetic fluids, magnetic recording materials, catalysts or catalyst carriers, microwave absorbing materials, and cell separation, Immunodetection, protein purification, nucleic acid separation, targeted drugs, immobilized enzymes and other fields. [0003] However, the wide application of magnetic particles is based on the success of micro-scale experiments. In order to better study the unique properties of magnetic particles, the sampling and removal of micro-scale magnetic particles obviously plays an increasingly important role. [0004] At present, there are two main methods for pipetting and sampling of trace magnetic particles, one...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): G01N1/04
Inventor张辉祝亚维陈闯
OwnerBEIJING JIAOTONG UNIV