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Syringa pubescens Turcz. bark extracts with protective effect on alcoholic liver injury

A technology of alcoholic liver injury and clove lobularis, which is applied in the research and development field of its pharmaceutical products, and can solve the problems of little research on clove lobularis

Inactive Publication Date: 2012-07-18
SHANDONG UNIV AT WEIHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although there are many studies on cloves, there are very few studies on cloves.

Method used

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  • Syringa pubescens Turcz. bark extracts with protective effect on alcoholic liver injury
  • Syringa pubescens Turcz. bark extracts with protective effect on alcoholic liver injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] 1, a kind of clove bark extract that has protective effect to alcoholic liver injury, it is characterized in that the preparation of this extract comprises following process:

[0012] Step (1): Weigh 100 g of dry coarse powder of clove bark, add water with an amount 8 times the weight of the coarse powder, soak for 8 hours, decoct for 1.5 hours, vacuum filter after decoction, and collect the filtrate;

[0013] Step (2): decoct the filter residue of the dried and coarse powder of Lilac bark in step (1) with water for 1 hour, then ultrasonically for 1 hour at a temperature of 30°C and a power of 80W, and vacuum filter to collect the filtrate;

[0014] Step (3): Combine the filtrates in steps (1) and (2), concentrate the filtrate into an extract, dry the extract, and pulverize to obtain 19.6 g of the bark extract of Cloves cloves.

[0015] 2. The extract is used to prepare a pharmaceutical preparation that has a protective effect on alcoholic liver damage.

Embodiment 2

[0017] 1, a kind of clove bark extract that has protective effect to alcoholic liver injury, it is characterized in that the preparation of this extract comprises following process:

[0018] Step (1): Weigh 200 g of dry coarse powder of clove bark, add water with an amount 10 times the weight of the coarse powder, soak for 10 hours, decoct for 2 hours, vacuum filter after decoction, and collect the filtrate;

[0019] Step (2): decoct the filter residue of the dried coarse powder of Lilac bark in step (1) with water for 1.5 hours, then ultrasonically for 1.5 hours at a temperature of 30°C and a power of 80W, and vacuum suction to collect the filtrate;

[0020] Step (3): Combine the filtrates in steps (1) and (2), concentrate the filtrate into an extract, dry the extract, and pulverize to obtain 37.3 g of the bark extract of Cloves cloves.

[0021] 2. The extract is used to prepare a pharmaceutical preparation that has a protective effect on alcoholic liver damage.

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Abstract

The invention belongs to the technical field of research and development of medical products. The invention relates to syringa pubescens Turcz. bark extracts with protective effect on alcoholic liver injury. The extracts are prepared by the following steps of: weighing dry coarse powder of syringa pubescens Turcz. barks, soaking the coarse powder in water with weight being 8-10 times that of the coarse powder for 8-10 hours, decocting the solution for 1.5-2 hours, carrying out vacuum filtration after decoction and collecting the filtrate; adding water to decoct the filter residues for 1-1.5 hours, then carrying out ultrasonic processing for 1-1.5 hours under the conditions that the temperature is 30 DEG C and the power is 80W, carrying out vacuum filtration and collecting the filtrate; and mixing the filtrate, concentrating the merged filtrate to extract, drying the extract and grinding the extract, thus obtaining the syringa pubescens Turcz. bark extracts. The extracts are used for preparing the pharmaceutical preparations with protective effect on alcoholic liver injury.

Description

technical field [0001] The invention belongs to the technical field of research and development of pharmaceutical products. The invention relates to an extract of clove bark which has protective effect on alcoholic liver injury. Background technique [0002] Syringa Pubescens Turcz, also known as hairy (leaf) clove, sparrow flower, Qiaoling flower, is a plant of the genus Syringa in the family Oleaceae (oleaceaceae), distributed in Liaoning, Hebei, Henan, Shanxi, Shaanxi and Gansu. About 2.5m high, young branches grayish brown, pilose. Leaves ovate or elliptic-ovate, entire, ciliate. Panicles are loose, lateral, lavender; flowering period from late April to early May; autumn from late July to early August. For a long time, folks have used its flower tea to treat chronic hepatitis, enteritis, esophageal cancer, liver cirrhosis, liver cancer and other diseases. The curative effect is remarkable. But it has not been included in the Pharmacopoeia so far. At present, although...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61P1/16A61K129/00
Inventor 张崇禧张成城侯欣池徐蕊郑友兰
Owner SHANDONG UNIV AT WEIHAI
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