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Capsule shell and preparation method thereof

A technology of capsule shell and capsule shell, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve problems such as intestinal irritation, and achieve the effects of slowing down irritation, avoiding bitter taste and smooth surface.

Active Publication Date: 2014-01-22
SHENGQUAN HEALTANG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above methods use plant-derived hydroxypropyl methylcellulose and chitin to replace the gelatin components in the original process, the stimulation of the intestinal tract by the drug itself is not avoided, and the bitterness produced by the capsule shell during swallowing can't avoid

Method used

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  • Capsule shell and preparation method thereof
  • Capsule shell and preparation method thereof
  • Capsule shell and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Take 37g of gelatin, 12.5g of water, 50g of L-arabinose, and 0.5g of glycerin, mix them evenly, and heat to 80°C to form a glue solution; shape it by dipping in glue, and dry it at 30°C to obtain a capsule shell.

Embodiment 2

[0038] Take 70g of hydroxymethyl cellulose, 17.5g of water, 1g of L-arabinose, and 11.5g of acetic acid, mix them evenly, and heat to 90°C to form a glue solution; shape it by dipping in glue, and dry it at 40°C to obtain a capsule shell.

Embodiment 3

[0040] Take 55g of agar, 15g of water, 25g of L-arabinose, and 5g of titanium dioxide, mix them evenly, and heat to 85°C to form a glue solution; shape it by dipping in glue, and dry it at 35°C to obtain a capsule shell.

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PUM

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Abstract

The invention relates to a capsule shell and a preparation method thereof. The capsule shell comprises 1-50 weight percent of L-arabinose. The capsule shell contributes to relieving stimulation of drugs to the intestinal tract and shortening the drug absorption time.

Description

technical field [0001] The invention relates to a capsule shell, in particular to a capsule shell containing L-arabinose. Background technique [0002] Capsule shell is an egg-shaped hollow shell used to contain solid powder and granules. It has good bioavailability and can dissolve quickly, reliably and safely. It is mainly used in medicine and pharmaceutical industries. Medical capsule shells are mainly used to contain solid medicines, such as self-made powders, health products, pharmaceuticals, etc. Capsule shells are mostly made of gelatin after refined treatment and auxiliary materials such as starch. If some drugs that have a greater stimulating effect on the stomach are put into the capsule shell, since the stomach does not absorb starch, the capsule will carry the drugs into the small intestine and be absorbed directly, avoiding the stimulation of the drugs on the stomach. However, after the capsule shell is dissolved, irritation of the intestinal tract by the drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/26A61K9/48
Inventor 唐地源刘顶王恩华
Owner SHENGQUAN HEALTANG CO LTD
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