Novel haemostatic composition

A technology of composition and water paste, applied in the direction of drug combination, blood disease, active ingredient of alkali/alkaline earth metal chloride, etc., can solve problems such as inability to use, limit dentist's working time, loss of consistency and effectiveness

Inactive Publication Date: 2014-03-26
LESAGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented product contains two components: one makes up more solidly than usual when mixed together but still works well at treatments like drilling teeth. It also prevents loss of strength during procedures such as removing bone tissue from root holes.

Problems solved by technology

The technical problem addressed in this patented technology relating to improving the performance of prosthetic implants involves creation of a stable and effective permanent cavity around the root canal without causing pain or swelling. Additionally, there needs to have access to both liquid medicines like calcium salt solutions and other agents suitable for treatments involving inflammation caused by bacteria or algae.

Method used

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  • Novel haemostatic composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] Step 1: In a 20-liter beaker made of low-density polyethylene, mix 10.757 liters of purified water according to the European Pharmacopoeia 6.3 standard (01 / 2009:0008) and 3 kg of aluminum chloride hexahydrate (Panreac), and use Stirring for 10 minutes with a turbine pneumatic agitator. Due to the exothermic nature of the reaction between water and aluminum chloride, all necessary precautions known to those skilled in the art must be used.

[0099] Then, under stirring, 2.6 g of patent blue (Spectracol) was gradually added into the vortex of the above mixture, and the resulting mixture was stirred for 10 minutes with a pneumatic stirrer until the solution was uniform.

[0100] While still stirring, add 2 kg of glycerin (La Cooper) to the vortex of the mixture and use a pneumatic stirrer to continue stirring for another 10 minutes.

[0101] Step 2: Put all the mixture prepared in step 1, 3.1kg PC389 carrageenan and 1.14 kg of kaolinite clay were introduced into a kettle equipp...

Embodiment 2-3

[0105] The various hemostatic compositions of the present invention were prepared according to the similar process as described in Example 1. In Table I below, the composition of each material used is given as a weight percentage relative to the total weight of the composition.

[0106] Table I

[0107]

[0108] (1) Sold by FMC BIOPOLYMERE PC389.

Embodiment 4

[0109] Example 4: Proof of the physical and chemical properties of the composition of the present invention

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Abstract

The present invention relates to a novel haemostatic composition which is particularly useful for ensuring proper haemostasis and keeping a sulcus open after a gingivectomy procedure. According to the invention, said composition is provided in the form of an extrudable hydrophilic paste and contains, expressed in weight percentage relative to the total weight of said composition: 5 to 15 % of an astringent, preferably aluminium chloride; 2 to 15 % of kaolinite clay, preferably kaolin; 10 to 20 % of a texturising agent including one or more natural polysaccharide(s) having a gelling or thickening capacity, optionally combined with plant fibres; 50 to 70 % of water; 0 to 20 % of a humectant, the total amount of water and humectant being 55 to 75 wt % relative to the total weight of the composition. The invention can be used in the dental field.

Description

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Claims

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Application Information

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Owner LESAGE
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