A kind of pharmaceutical composition for treating benign prostatic hyperplasia

Abstract

The invention relates to a medicinal composition for treating benign prostatic hyperplasia. The medicinal can be tablets, capsules, granules and the like prepared from alfuzosin or pharmaceutically acceptable salt thereof with effective dosage and plantain seed alcohol extract in a mass ratio of 1:(1-10000) by the amount of alfuzosin. Pharmacological researches on the medicinal composition discover that the medicinal composition for treating benign prostatic hyperplasia has perfect treatment effect, and can remarkably inhibit benign prostatic hyperplasia of a rat subjected to orchiectomy. The alfuzosin or pharmaceutically acceptable salt and the plantain seed alcohol extract have a synergetic effect, and achieve an unexpected technical effect.

Description

technical field

[0001] The invention belongs to the technical field of medicine and relates to a pharmaceutical composition for treating benign prostatic hyperplasia. Background technique

[0002] Benign prostatic hyperplasia (BPH) is the most common benign disease that causes voiding disorders in middle-aged and elderly men. The main reason is the increase of age and the existence of functional testis, and the urinary obstruction caused by it has two main reasons: one is that the testosterone produced by the testis is converted into dihydrotestosterone under the action of 5α reductase, which acts on The prostate enlarges the prostate gland. The protruding gland protrudes into the bladder, compressing the urethra and causing mechanical obstruction of the bladder outlet. On the other hand, the bladder neck, posterior urethra, prostatic body, and capsule are rich in α-receptors. Due to the stimulation of mechanical obstruction, the α-receptors in the above-mentioned parts ar...

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