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A ganoderma preparation with triple effects of inhibiting prostatic hyperplasia, protecting liver and improving immunity

A technology of prostatic hyperplasia and Ganoderma lucidum, which is applied to medical preparations containing active ingredients, organic active ingredients, pharmaceutical formulations, etc., can solve problems such as liver damage, toxic and side effects, and achieve the improvement of chronic hepatitis, inhibition of benign prostatic hyperplasia, and prevention of disease. effect of recurrence

Active Publication Date: 2021-06-25
SHANGHAI ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, liver protection drugs themselves also have potential liver damage problems
The hepatoprotective drugs currently developed are mainly synthetic drugs, and these drugs have relatively high toxicity and side effects. It is particularly urgent to find natural drugs without toxic side effects for the prevention and treatment of liver diseases.

Method used

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  • A ganoderma preparation with triple effects of inhibiting prostatic hyperplasia, protecting liver and improving immunity
  • A ganoderma preparation with triple effects of inhibiting prostatic hyperplasia, protecting liver and improving immunity
  • A ganoderma preparation with triple effects of inhibiting prostatic hyperplasia, protecting liver and improving immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The Ganoderma lucidum preparation components of the present invention have triple functions of inhibiting prostatic hyperplasia, protecting the liver, and improving immunity. The acid G content is 0.0005%, the ganoderma acid D content is 0.0005%, the ganoderma ketotriol content is 0.0008%, and the ganoderma acid DM content is 0.0005%.

[0030] The preparation method of the Ganoderma lucidum preparation with the triple effects of inhibiting prostatic hyperplasia, protecting the liver and improving immunity:

[0031] Dry and crush 1 part (parts by weight) of Ganoderma lucidum No. 1 fruiting body to 40 mesh, add 8 times the volume of 80% ethanol, soak for 2 hours, and heat reflux extraction at 80°C for 2 times, the first time is 2 hours, the second time is 1 hour, Collect the filter residue by filtration, concentrate the filtrate in vacuum at 60°C according to the volume of 1:1 to obtain a concentrated solution, remove impurities by high-speed centrifugation, continue to c...

Embodiment 2

[0046] The components of the Ganoderma lucidum preparation with the triple effects of inhibiting prostatic hyperplasia, protecting the liver, and improving immunity include, by mass percentage, controlling the Ganoderma lucidum polysaccharide content of 2.9%, the Astragalus polysaccharide content of 2.0%, the Ganoderma acid A content of 0.001%, and Ganoderma lucidum The acid G content is 0.0004%, the ganoderma acid D content is 0.0005%, the ganoderma ketotriol content is 0.0006%, and the ganoderma acid DM content is 0.0005%.

[0047] The preparation method of the Ganoderma lucidum preparation with the triple effects of inhibiting prostatic hyperplasia, protecting the liver and improving immunity:

[0048] Dry and crush 1 part (parts by weight) of Ganoderma lucidum No. 1 fruiting body to 40 mesh, add 8 times the volume of 95% ethanol, soak for 2 hours, and heat reflux extraction at 80°C for 2 times, the first time is 2 hours, the second time is 1 hour, Collect the filter residu...

Embodiment 3

[0062] Embodiment 3 (comparative example):

[0063] The components of the Ganoderma lucidum preparation with three functions of inhibiting prostatic hyperplasia, protecting the liver and improving immunity include, by mass percentage, the content of Ganoderma lucidum polysaccharide in the Ganoderma lucidum preparation is 2.18%, and the content of Astragalus polysaccharide in the Ganoderma lucidum preparation is 1.90%.

[0064] The preparation method of the Ganoderma lucidum preparation with the triple effects of inhibiting prostatic hyperplasia, protecting the liver and improving immunity:

[0065] Dry and crush 1 part (parts by weight) of Hunong Ganoderma lucidum No. 1 fruiting body to 40 mesh, add 10 times the volume of water, extract twice at 100°C, each time for 1 hour, add a small amount of water to rinse at the end, filter and combine the water extracts , 1:1 volume concentration in vacuum at 60°C, high-speed centrifugation to remove impurities, the concentrated solution...

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Abstract

The invention discloses a Ganoderma lucidum preparation with triple effects of inhibiting prostatic hyperplasia, protecting the liver and improving immunity, which comprises, in terms of mass percentage, the content of Ganoderma lucidum polysaccharides of 2.5-3.5%, the content of Astragalus polysaccharides of 1.8-2.4%, and Ganoderma acid A The content of ganoderma acid G is 0.0008-0.0012%, the content of ganoderma acid G is 0.0004-0.0006%, the content of ganoderma acid D is 0.0004-0.0006%, the content of ganoderma ketotriol is 0.0007-0.0009%, and the content of ganoderma acid DM is 0.0004-0.0006%. On the basis of inhibiting prostatic hyperplasia and protecting the liver, the ganoderma lucidum preparation is compatible with Astragalus membranaceus to synergistically exert the effects of various medicinal materials on inhibiting prostatic hyperplasia, protecting the liver and nourishing the liver, and improving immunity. The obtained ganoderma lucidum tablet can inhibit prostatic hyperplasia , Improve chronic hepatitis, and effectively prevent the recurrence and deterioration of the disease.

Description

technical field [0001] The invention belongs to the technical field of medicine and health products, and in particular relates to a ganoderma preparation with triple functions of inhibiting prostatic hyperplasia, protecting the liver and improving immunity. Background technique [0002] Benign prostatic hyperplasia (Benign Prostatic Hyperplasia, BPH) is the excessive proliferation of prostate epithelial and stromal cells, resulting in increased prostate volume, which causes clinical symptoms such as urinary frequency and urgency. Benign prostatic hyperplasia and prostate cancer and prostatitis are known as the three major diseases of the prostate. Benign prostatic hyperplasia usually occurs after the age of 40, and the incidence is greater than 50% at the age of 60, and as high as 83% at the age of 80. Among the elderly male population , Prostate disease has become the disease with the highest incidence rate. With the development of my country's aging process, the proportio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/575A61K36/481A61P13/08A61P1/16A61P37/04
Inventor 张劲松贾薇汪雯翰徐宾杨妍徐锦唐传红庄海宁杨焱刘艳芳
Owner SHANGHAI ACAD OF AGRI SCI
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