A method for obtaining the delay time of contrast agent

Abstract

The invention relates to a method for obtaining the delay time of a contrast agent. Automatically identify the contrast agent sample in the image, accurately locate the center point of the sample to calculate the radius of the sample test tube, and automatically select the ROI based on the center point of the test tube according to the radius of the test tube, calculate the average value of the pixel signal in the ROI, and the experimental standard deviation. Finally, nonlinear fitting is performed on the automatically extracted signals to accurately, quickly and efficiently calculate the spin-lattice relaxation time T1 and spin-spin relaxation time T2 values ​​of the contrast agent. The process of identifying multiple samples in the image and selecting the sample ROI is a computer-automated process that does not require manual processes. The positioning accuracy, ROI shape consistency, and result accuracy are much higher than traditional methods; this method is from ROI selection, ROI signal extraction to The entire process of nonlinear fitting is a fully automated process, and its time efficiency is much higher than that of traditional methods.

Description

technical field [0001] The invention relates to the field of magnetic resonance imaging, in particular to a method for automatically extracting signals in magnetic resonance contrast agent imaging and using them to fit and calculate the delay time of contrast agents. Background technique [0002] Image contrast in MRI reflects the difference in signal intensity between two tissues, and contrast enhancement is the process of changing the signal intensity. Contrast agents, also known as contrast agents (Contrast agents), are agents that can change the physical properties of tissues, thereby affecting physical parameters and enhancing image contrast. Magnetic resonance contrast agents alter image contrast by altering the local magnetic environment of tissue. In magnetic resonance imaging, the magnetic resonance signal generated by protons and its spin-lattice delay time (longitudinal delay time) T1 and spin-spin delay time (transverse delay time) T2 determine the different tis...

AI Technical Summary

Problems solved by technology

[0008] The present invention aims at the problems of time-consuming, low efficiency, and subjectivity in obtaining contrast agent delay time in current image processing methods, and proposes a method for obtaining contrast agent delay time, which can automatically identify contrast agent samples in images, accurately Locate the center point of the sample to calculate the radius of the sample test tube, and automatically select the ROI based on the center point of the test tube according to the radius of the test tube, calculate the average value of the pixel signal in the ROI, and the experimental standard deviation

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