Multi-shot scan protocols for high-resolution mri incorporating multiplexed sensitivity-encoding (muse)

A multi-shot, high-resolution technology that can be used in applications, image analysis, image enhancement, etc., to solve problems such as implicated imaging throughput

Active Publication Date: 2015-02-25
DUKE UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A potential problem with the variable density helical imaging approach is that imag

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  • Multi-shot scan protocols for high-resolution mri incorporating multiplexed sensitivity-encoding (muse)
  • Multi-shot scan protocols for high-resolution mri incorporating multiplexed sensitivity-encoding (muse)
  • Multi-shot scan protocols for high-resolution mri incorporating multiplexed sensitivity-encoding (muse)

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Embodiment Construction

[0078] For the purposes of promoting an understanding of the principles of the disclosure, reference will now be made to the preferred embodiments and specific language will be used to describe the same. It should be understood, however, that no limitation of the scope of the disclosure is thereby intended and that such alterations and further modifications of the disclosure as illustrated herein are contemplated as would normally occur to those skilled in the art to which this disclosure pertains.

[0079] The articles "a" and "a" are used herein to refer to one or to more than one (ie at least one) of the grammatical object of the article. By way of example, "an element" means at least one element and may include more than one element.

[0080] Unless otherwise defined, all technical terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs.

[0081] The present invention will now be described more fu...

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Abstract

Diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) using a new technique, termed multiplexed sensitivity encoding with inherent phase correction, is proposed and implemented to effectively and reliably provide high-resolution segmented DWI and DTI, where shot-to-shot phase variations are inherently corrected, with high quality and SNR yet without relying on reference and navigator echoes. The performance and consistency of the new technique in enabling high-quality DWI and DTI are confirmed experimentally in healthy adult volunteers on 3 Tesla MRI systems. This newly developed technique should be broadly applicable in neuroscience investigations of brain structure and function.

Description

[0001] related application [0002] This application claims the benefit of and priority to US Provisional Application No. 61 / 665494, filed June 28, 2012, the contents of which are hereby incorporated by reference as if fully set forth herein. [0003] Federal Statement of Support [0004] This invention was made with government support under grant numbers R01 NS 074045, R01 EB 009483 and R01 NS 075017 awarded by the National Institute of Health. The US Government has certain rights in this invention. Background technique [0005] The advent of diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) has provided the means to investigate the integrity of white matter in the human brain and its impact on neurological function via the investigation of water diffusion. Quantitative mapping of tissue diffusion properties such as apparent diffusion coefficient (ADC) and fractional anisotropy (FA) derived from DWI and DTI scans is sensitive to pathological changes in ...

Claims

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Application Information

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IPC IPC(8): A61B5/055
CPCG01R33/5611G01R33/5616G01R33/56509G01R33/56341G01R33/543A61B5/055G01R33/5615G06T5/001G06T5/002G06T7/0012G06T7/20H04N7/18
Inventor N-K.陈A.W.宋
Owner DUKE UNIV
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