Method for clarifying Chinese herbal preparation for treating psoriasis

A traditional Chinese medicine preparation, psoriasis technology, applied in the field of medicine, can solve the problems of large alcohol consumption, high equipment investment, long process time, etc., and achieve the effects of reducing solids, short process cycle, and improving impurity removal efficiency

Inactive Publication Date: 2016-08-24
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a fast and efficient clarification method for the water extract of traditional Chinese medicine preparations for the treatment of psoriasis, which solves the problem

Method used

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  • Method for clarifying Chinese herbal preparation for treating psoriasis
  • Method for clarifying Chinese herbal preparation for treating psoriasis
  • Method for clarifying Chinese herbal preparation for treating psoriasis

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Experimental program
Comparison scheme
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Embodiment Construction

[0020] 1. Reagent preparation

[0021] Such as Figure 1-6 As shown, a clarification method of the traditional Chinese medicine preparation for the treatment of psoriasis of the present invention, the traditional Chinese medicine preparation for the treatment of psoriasis is conventionally decocted and extracted, the extract is concentrated under reduced pressure, placed in a 60°C water bath, and 4% of the volume of the water extract is added first Type II ZTC1+1 natural clarifier B component, add 2% volume of A component after 1h, and stir for 1 minute every half hour to make impurity components coagulate and precipitate, and then centrifuge at 4000r / min for 10min in a centrifuge, take supernatant.

[0022] Among them, type II ZTC1+1 natural clarifier:

[0023] For component A, accurately measure 1.0g type II ZTC1+1 natural clarifier, add a small amount of distilled water, stir to form a paste, then add distilled water to prepare 100mL viscose solution, swell for 24 hours, ...

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Abstract

The invention discloses a clarification method of a traditional Chinese medicine preparation for treating psoriasis, which comprises adding 4% of natural clarifier B component and 2 % component A, in a water bath at 60°C, with an interval of 1h between the two components, and stirring for 1min every 0.5h, then centrifuged, and the supernatant was taken. The clarification and impurity removal method adopted in the present invention does not require any special equipment, has low equipment investment and simple operation process, and overcomes the defects of the traditional alcohol precipitation and impurity removal method, such as large alcohol consumption, time-consuming process, and cumbersome ethanol recovery process. At the same time, the results of cell experiments showed that both the traditional Chinese medicine preparation for the treatment of psoriasis and the unmodified Yinxie Ling Fang had the effect of inhibiting the proliferation of keratinocytes. The taste of the medicine was simplified and reasonable, and it was less toxic than the chemical drug methotrexate.

Description

technical field [0001] The invention relates to a clarification and impurity removal process of a traditional Chinese medicine preparation for treating psoriasis, and belongs to the technical field of medicine. Background technique [0002] Psoriasis is an immunologically abnormal chronic proliferative skin disease determined by polygenic inheritance and stimulated by multiple environmental factors, with the characteristics of recurrent attacks. The etiology and pathogenesis of psoriasis are very complicated, and there is currently no curative drug. Studies have shown that psoriasis can significantly increase the incidence of major diseases such as cardiovascular and cerebrovascular diseases, and increase the psychological burden of patients. In the treatment of psoriasis, traditional Chinese medicine can not only effectively relieve symptoms and reduce the recurrence rate, but also has low toxic and side effects, reasonable price and suitable for long-term use. [0003] Y...

Claims

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Application Information

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IPC IPC(8): B01D21/01
Inventor 卢传坚王冬梅朱伟
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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