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Medicinal composition for treating bladder cancer and preparation method of medicinal composition

A composition and technology for bladder cancer, applied in the field of pharmaceutical composition for treating bladder cancer and its preparation

Inactive Publication Date: 2016-11-16
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently there is no effective treatment for bladder cancer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: The pharmaceutical composition for the treatment of bladder cancer and its preparation method

[0039] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating bladder cancer are: 30g of Kaporin, 470g of goose egg shell, 327g of asterite, 9g of liensinine, 5g of morroniside, and 1.5g of asiatic acid;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take Kaporin, goose egg shell, Viola halide, Liensinine, morroniside, and asiatic acid, mix them evenly, and use ethanol with a concentration of 36.5% by weight as a solvent, at 37.5°C Warm immersion extraction, the number of extractions is 22 times, each extraction time is 10 hours, and the amount of solvent used each time is 27 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.23, filter, the drug solution passes through...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for the treatment of bladder cancer and its preparation method

[0045] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating bladder cancer are: 25g of Kaporin, 480g of goose egg shell, 326g of asterite, 10g of liensinine, 4g of morroniside, and 2g of asiatic acid;

[0046] Preparation:

[0047] (1) According to the ratio of raw materials, take Kaporin, goose egg shell, Viola halide, Liensinine, morroniside, and asiatic acid, mix them evenly, and use ethanol with a concentration of 36.5% by weight as a solvent, at 37.5°C Warm immersion extraction, the number of extractions is 22 times, each extraction time is 10 hours, and the amount of solvent used each time is 27 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.23, filter, the drug solution passes through ...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition for the treatment of bladder cancer and its preparation method

[0051] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating bladder cancer are: 35g of Kaporin, 460g of goose egg shell, 328g of asterite, 8g of liensinine, 6g of morroniside, and 1g of asiatic acid;

[0052] Preparation:

[0053] (1) According to the ratio of raw materials, take Kaporin, goose egg shell, Viola halide, Liensinine, morroniside, and asiatic acid, mix them evenly, and use ethanol with a concentration of 36.5% by weight as a solvent, at 37.5°C Warm immersion extraction, the number of extractions is 22 times, each extraction time is 10 hours, and the amount of solvent used each time is 27 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates To a relative density of 1.23, filter, the drug solution passes th...

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PUM

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Abstract

The present invention discloses a medicinal composition for treating bladder cancer and a preparation method thereof. The raw material drug, which is prepared by proportioning, can be made into various dosage forms according to the conventional preparation process, and has a remarkable curative effect on bladder cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating bladder cancer and a preparation method thereof. Background technique [0002] Bladder cancer is the ninth most common malignant tumor in the world, and it is the most common tumor of the urinary system. Among them, 75% -85% are non-muscle invasive carcinomas (superficial carcinomas). Comprehensive treatment should be used in the treatment of bladder cancer. Postoperative recurrence of bladder cancer is an important factor affecting the prognosis of bladder cancer. The literature reports that the postoperative recurrence rate is as high as 50%-80%. Although postoperative intravesical chemotherapy or intravesical immunotherapy was used, the probability of postoperative tumor recurrence was 45%, and the probability of progression was 1.8%. At the same time, because the infusion drugs currently used to prevent the r...

Claims

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Application Information

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IPC IPC(8): A61K36/24A61P35/00A61K35/57A61K31/7048A61K31/56A61K31/4725A61K31/4375
CPCA61K36/24A61K31/4375A61K31/4725A61K31/56A61K31/7048A61K35/57A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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