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Composition containing scutellaria alpina extract

A technology of Scutellaria baicalensis extract and composition is applied in the field of compositions containing Scutellaria baicalensis extract, which can solve the problems of reduced immune activity, destruction of skin homeostasis, weakened skin moisturizing and barrier functions, etc., and achieves maintenance of skin homeostasis, maintenance of Anti-stress effect, effect of reducing the amount of EDN1

Inactive Publication Date: 2017-05-10
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Reduced immune activity induced by stress may lead to disruption of skin homeostasis, which in turn can impair skin moisturizing and barrier functions that protect the skin from harmful external factors

Method used

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  • Composition containing scutellaria alpina extract
  • Composition containing scutellaria alpina extract
  • Composition containing scutellaria alpina extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] [Example 1] Preparation of Alpine Scutellaria alpina (Scutellaria alpina) Extract

[0085] The flowers, leaves and stems of Scutellaria baicalensis are harvested, dried with hot air and crushed into powder. The resulting powder was extracted with ethanol / water solution, and then ethanol was removed by vacuum distillation. After adding glycerin and a preservative to the resulting concentrate, Scutellaria baicalensis was obtained by filtration. The Scutellaria baicalensis extract prepared according to the above method was purchased from DSM Nutritional Products Ltd. (4002 Basel, Switzerland) ( SCUTELLARIA AO) for the following test examples.

Embodiment 2

[0112] [Dosage Form Example 2] Tablet

[0113] 8 mg of the Scutellaria baicalensis extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 200 mg of galacto-oligosaccharides, 60 mg of lactose and 140 mg of maltose were mixed and a fluidized bed dryer was used. Then, after adding 6 mg of sugar ester, the mixture was prepared into tablets containing 500 mg of the composition according to the usual method.

Embodiment 3

[0114] [Dosage Form Example 3] Drink

[0115] Mix 8 mg of the Scutellaria baicalensis extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 10 g of glucose, 0.6 g of citric acid and 25 g of oligosaccharide syrup, and add 300 mL of purified water. 200 mL of the mixture was filled into bottles. Then, the drink was prepared by sterilizing at 130° C. for 4-5 seconds.

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PUM

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Abstract

The present invention relates to a composition containing a Scutellaria alpina extract as an active ingredient. The composition of the present invention exhibits effects of reducing the amount of endothelin 1 by containing a Scutellaria alpina extract, and reducing the overexpression of NK1R and EDN1 genes. Therefore, the Scutellaria alpina extract of the present invention can exhibit, by said effects, skin homeostasis maintenance and anti-stress effects, and thus can be widely used as a composition for maintaining skin homeostasis in the pharmaceutical or cosmetic field.

Description

technical field [0001] The present invention relates to a composition comprising an extract of Scutellaria baicalensis. Background technique [0002] Stress, known as the cause of all modern diseases, refers to: when a certain degree or higher degree of stimulation (regardless of the type of stimulation) acts on the body in a harmful way and poses a threat to the body, Nonspecific general adaptation syndrome as a response to this threat (Selye, H.: The stress of life, Toronto, LongnansGreen and Co., pp. 1-50, 1958). The causes of stress mainly include (1) physical factors: overwork, lack of sleep, trauma, poisoning, etc.; (2) external factors: natural environment, cultural situation, interpersonal relationships in the family or workplace, etc.; and (3) internal factors : Personality, psychological conflicts in life, trauma experienced by an infant or child, etc. [0003] When the stress lasts for a long time, it may cause physical diseases such as heart disease, gastric ul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K8/9789A23L33/105A61P17/00A23L33/00
CPCA61Q19/08A61K36/539A61K8/9789A61P17/00A61P17/16A61P37/04A61P43/00A61Q19/00A61K2800/74A61K2800/805A61K2236/33
Inventor 朴泌俊李昭希曹恩敬李泰龙
Owner AMOREPACIFIC CORP
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