Predictive tumor system based on next generation sequencing

A next-generation sequencing and tumor technology, which is applied in the direction of biological material pretreatment, microbial measurement/inspection, specific-purpose bioreactor/fermenter, etc., can solve problems such as low accuracy rate and incomplete screening range, and achieve Improve efficiency, speed, and predict accurate results

Inactive Publication Date: 2017-06-13
首度生物科技(苏州)有限公司 +1
View PDF10 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most testing institutions can only provide several specific genetic tumor screenings, the screening range is not comprehensive, and the prediction accuracy is relatively low

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Predictive tumor system based on next generation sequencing
  • Predictive tumor system based on next generation sequencing
  • Predictive tumor system based on next generation sequencing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The tumor prediction system based on next-generation sequencing of the present invention includes an anticoagulant blood collection tube 1 , a DNA extraction kit 2 , a next-generation sequencing device 3 and a gene mutation evaluation system 4 .

[0019] In this implementation, the anticoagulant blood collection tube is an EDTA anticoagulant blood collection tube, and 2ml of venous blood is collected through the EDTA anticoagulant blood collection tube. Whole blood DNA is extracted from blood coagulated in blood collection tubes. This DNA extraction kit is commercially available and will not be discussed in detail here.

[0020] In this embodiment, the next-generation sequencing device includes a library building module 31 and a sequencing module 32, and the sequencing module is an Illumina next-generation sequencing platform. Of course, the protection scope of the present invention is not limited to the Illumina next-generation sequencing platform. The library building...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A system for predicting tumors based on next-generation sequencing, including an anticoagulant blood collection tube for collecting blood, a DNA extraction kit, a next-generation sequencing device, and a gene mutation evaluation system. Extract whole blood DNA, the second generation sequencing device detects the sequence of the whole blood DNA, the gene mutation evaluation system analyzes the situation of gene mutation according to the sequence detected by the second generation sequencing device, and according to the tumorigenicity grade of the mutated gene And the dominant recessiveness of the gene predicts the risk level of tumor occurrence. The present invention adopts the second-generation sequencing platform second-generation sequencing device to sequence the gene, which is fast, so that the gene can be comprehensively sequenced, the tumor can be comprehensively screened, and the risk level of the tumor can be predicted through the gene mutation evaluation system, so that customers can do it as soon as possible. get ready. Analyze the situation of gene mutation, and predict the risk level of tumor occurrence according to the tumorigenicity level of the mutated gene and the dominant recessiveness of the gene, and fully consider the impact of the mutated gene on the occurrence of tumor, thus making the prediction more accurate.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to a next-generation sequencing-based tumor prediction system. Background technique [0002] Hereditary tumors are caused by mutations in specific disease-causing genes (such genes are called hereditary tumor-associated genes) and are clustered in families, accounting for about 5% to 10% of cancers, including gastric cancer, melanoma, Colorectal cancer, breast cancer, ovarian cancer, etc. [0003] The latest study in 2014 analyzed the spectrum of cancer epidemics in China, which showed that based on the average life expectancy of 74 years, the probability of each person suffering from malignant tumors in their lifetime is 22%. People with inherited tumor-associated gene mutations have an increased risk of malignancy. At present, most testing institutions can only provide several specific genetic tumor screenings, the screening range is not comprehensive, and the predicti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34
CPCC12Q1/6869C12Q2565/519
Inventor 雷建强唐元华徐健
Owner 首度生物科技(苏州)有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap