Application of Asystasia gangetica ssp. Micrantha in preparation of drug for preventing and/or treating neurodegenerative disease and drug

A neurodegenerative, one-hundred-thousand-error technology, applied to nervous system diseases, drug combinations, medical formulas, etc., can solve problems such as no medical records, and achieve the effect of delaying death

Active Publication Date: 2017-11-21
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Distributed abroad in Africa, Southwest Asia, Indian Ocean Islands and Madagascar, naturalized in Taiwan and Guangdong in recent years, there is no record of its medicinal use in China

Method used

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  • Application of Asystasia gangetica ssp. Micrantha in preparation of drug for preventing and/or treating neurodegenerative disease and drug
  • Application of Asystasia gangetica ssp. Micrantha in preparation of drug for preventing and/or treating neurodegenerative disease and drug
  • Application of Asystasia gangetica ssp. Micrantha in preparation of drug for preventing and/or treating neurodegenerative disease and drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The present embodiment provides a kind of medicine, and this medicine is mainly prepared by the following steps:

[0054] Weigh 20g of Xiaohua Shiwancuo, put it in a conical flask, add 300ml of 95% ethanol aqueous solution to the conical flask, ultrasonically extract at 60°C for 30min, filter, concentrate into a extract with a rotary evaporator, and evaporate in an evaporating dish Dry and dry in a constant temperature oven (50°C) until constant weight.

Embodiment 2

[0056] The present embodiment provides a kind of medicine, and this medicine is mainly prepared by the following steps:

[0057] Weigh 10g of Xiaohua Shiwancuo, put it in a conical flask, add 50ml of 30% ethanol aqueous solution into the conical flask, ultrasonically extract at 30°C for 15min, filter, concentrate under reduced pressure to form an extract, then place it in an evaporating dish and evaporate to dryness. Dry in a constant temperature oven (50°C) until constant weight.

Embodiment 3

[0059] The present embodiment provides a kind of medicine, and this medicine is mainly prepared by the following steps:

[0060] Weigh 10g of Xiaohua Shiwancuo, put it in a conical flask, add 200ml 60% 1,2-propanediol aqueous solution to the conical flask, ultrasonically extract at 90°C for 60min, filter, concentrate under reduced pressure to form an extract, and then vacuum freeze-dry to constant weight.

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Abstract

The invention relates to the field of drugs, in particular to application of Asystasia gangetica ssp. Micrantha in preparation of a drug for preventing and / or treating a neurodegenerative disease and a drug. The invention relates to the application of the Asystasia gangetica ssp. Micrantha in preparation of the drug for preventing and / or treating the neurodegenerative disease. The inventor discovers that the Asystasia gangetica ssp. Micrantha and the extract thereof can protect nerve cells from being injured, and therefore death of nerve cells is stopped or delayed. It proves that by the drug which contains the Asystasia gangetica ssp. Micrantha, HT-22 nerve cells can keep healthful and can be proliferated; and it shows that the Asystasia gangetica ssp. Micrantha can be used for preparing a drug for treating or preventing central neurons from gradual denaturation and apoptosis.

Description

technical field [0001] The invention relates to the field of medicines, in particular to the application and medicine of Xiaohua Shiwancuo in the preparation of medicines for preventing and / or treating neurodegenerative diseases. Background technique [0002] The micrantha micrantha (Asystasiagangetica subsp. micrantha (Nees) Ensermu) is a dicotyledonous plant of the genus Asystasiagangetica subsp. micrantha (Nees) Ensermu, which can be harvested throughout the year. It is distributed in Africa, Southwest Asia, Indian Ocean Islands and Madagascar abroad, and has been naturalized in Taiwan and Guangdong in recent years. There is no record of its medicinal use in China. In addition, florets can be eaten as wild vegetables, and their toxic and side effects are almost negligible. Contents of the invention [0003] The purpose of the present invention is to provide an application and medicine of Xiaohua Shiwancuo in the preparation of medicines for the prevention and / or treatm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/19A61P25/28A61P25/14A61P25/16
CPCA61K36/19A61K2236/331A61K2236/333A61K2236/35A61K2236/51
Inventor 何细新银巍彭光天陈文礼张翠仙
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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