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A kind of facial acne clearing compound essential oil and preparation method thereof

A compound essential oil and acne-clearing technology, applied in the field of chemical industry, can solve the problems of lack of safety limit regulations and hidden dangers, and achieve the effects of enhancing acne-clearing effect, better effect and fast absorption by the human body

Active Publication Date: 2020-09-08
南京紫源康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As the key technology for preparing high-purity shikonin has not yet been industrialized, domestic new drug products using shikonin as raw materials have not yet officially entered the market. The 2010 edition of the Chinese Pharmacopoeia still contains some varieties containing PAs but lacking safety limit regulations , which also includes comfrey, leaving hidden dangers for clinical application

Method used

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  • A kind of facial acne clearing compound essential oil and preparation method thereof
  • A kind of facial acne clearing compound essential oil and preparation method thereof
  • A kind of facial acne clearing compound essential oil and preparation method thereof

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preparation example Construction

[0026] The extraction process of shikonin can adopt the method disclosed in the patent (application number: 201610308625.3) "Preparation method of an antibacterial and anti-inflammatory compound". The extraction steps include:

[0027] (1) Enzymolysis: Pulverize comfrey, disperse in water, add compound enzyme preparation for enzymolysis; in terms of mass percentage, the composition of the compound enzyme preparation is: cellulase, 50-80%; pectinase, 15-30%; the rest is xylanase; the average enzyme activity of the compound enzyme preparation is 10,000-50,000 units; the added amount of the compound enzyme preparation is 0.2-0.8% of the mass of comfrey;

[0028] (2) Alkaline water extraction: after enzymatic hydrolysis, add sodium hydroxide to the system for extraction to obtain the comfrey extract;

[0029] (3) Separation and purification: after filtering the shikonin extract, the shikonin crude product was obtained by alumina column chromatography, methanol analysis, concentrat...

Embodiment 1

[0039] Weigh each component by weight as follows:

[0040]

[0041] Fully mix 0.02 parts of shikonin with 7 parts of tea tree essential oil and 3 parts of lavender essential oil, then evenly mix with 89.98 parts of grape seed oil, and finally fill it to obtain the facial acne clearing compound essential oil.

Embodiment 2

[0043] Weigh each component by weight as follows:

[0044]

[0045] Fully mix 0.08 parts of shikonin with 3 parts of tea tree essential oil and 16 parts of lavender essential oil, then evenly mix with 80.92 parts of jojoba oil, and finally fill it to obtain the facial acne clearing compound essential oil.

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Abstract

The invention discloses a facial pox clearing compound essential oil and a preparing method thereof. The facial pox clearing compound essential oil comprises, by mass, 0.02-1.5 parts of shikonin, 0.5-8.5 parts of tea tree essential oil, 0.5-16 parts of lavender essential oil and 75-90 parts of base oil. The invention further discloses a preparing method for facial pox clearing compound essential oil. According to the facial pox clearing compound essential oil and the preparing method thereof, pure natural essential oil is adopted, the fact that the essential oil is a small molecule material is utilized, permeability is good, human body absorbing is fast, the shikonin can rapidly reach a deep cell layer under guidance and action of the essential oil to look for pox source and inhibit activity of the pox, so that the generative capacity of pox muscle is declined rapidly, the pox muscle can be improved in a short term, safe and no =stimulation effects are achieved, long-term use effect is good; and on the other hand, the base oil is mixed according to a certain percentage, the synergy effect is achieved, and the pox clearing effect is further enhanced.

Description

technical field [0001] The invention relates to the technical field of chemical industry, in particular to a face acne-clearing compound essential oil added with shikonin and a preparation method thereof. Background technique [0002] Acne, also known as acne, is mainly closely related to factors such as excessive sebum secretion, pilosebaceous duct blockage, bacterial infection and inflammatory response. Puberty or mental stress, irregular work and rest, unbalanced diet, or before and after menstruation, etc., will have an impact on the nervous system and endocrine, resulting in fluctuations in hormone levels, causing irregular sebum secretion (excessive local sebum secretion) and skin irritation. Cell metabolism disorder (old dead skin cells accumulate, clog pores), resulting in acne. Treatment to suppress the inflammatory response and prevent microbial infection is required. Western medicine antibacterial drugs are mostly antibacterial drugs and antifungal drug antibiot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/35A61K8/92A61Q19/00A61K36/61A61K36/87A61P17/10A61K31/122
CPCA61K8/355A61K8/922A61K31/122A61K36/53A61K36/61A61K36/87A61Q19/00A61K2300/00
Inventor 吴琦魏元刚钟慧金显友易铭
Owner 南京紫源康医药科技有限公司
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