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Method and device for treating blood cholesterol disorders

A cholesterol and total cholesterol technology, applied in blood diseases, extracellular fluid diseases, blood circulation treatment, etc., can solve problems such as unsatisfactory effects

Inactive Publication Date: 2018-03-06
GRIFOLS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such an effect may be undesirable, especially in patients with borderline and / or low HDL levels

Method used

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  • Method and device for treating blood cholesterol disorders
  • Method and device for treating blood cholesterol disorders
  • Method and device for treating blood cholesterol disorders

Examples

Experimental program
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Effect test

Embodiment approach

[0107] 1. Use of a plasmapheresis device in the manufacture of an apparatus for the treatment of a cholesterol disorder, wherein said treatment comprises:

[0108] A first treatment regimen comprising two or more rounds of plasmapheresis is administered to a patient with abnormal total cholesterol levels, abnormal LDL levels, and / or abnormal HDL levels as measured prior to treatment, wherein the first treatment regimen reduces LDL levels in patients with LDL levels and / or increased HDL levels in patients with abnormal HDL levels, and

[0109] wherein each subsequent round of said first treatment regimen maintains a new lower total cholesterol level, lower LDL level and / or higher HDL level.

[0110] 2. The use according to embodiment 1, wherein each subsequent round of the first treatment regimen is performed about 2 days to about 4 days after the previous round.

[0111] 3. The use according to embodiment 1, wherein each subsequent round of the first treatment regimen is perf...

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Abstract

The present invention refers to a composition and a device comprising whole blood cells for treating cholesterol disorders for use in a method comprising administering at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnormal total cholesterol, abnormal LDL levels and / or abnormal HDL levels prior to treatment. Treatment with said composition and device results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnormal HDL levels. Each subsequent round of plasmapheresis is conducted weekly,but no more than twice per week.

Description

[0001] This application is a divisional application of a Chinese patent application with an application date of March 12, 2013, an application number of "201310078574.6", and an invention title of "Use and device for treating blood cholesterol disorders". technical field [0002] The present invention relates to uses and devices for removing total cholesterol, low density lipoprotein cholesterol (LDL) and / or high density lipoprotein cholesterol (HDL) from whole blood. In particular, the device comprises means for separating red blood cells from plasma from said whole blood. Background technique [0003] Plasmapheresis is a common medical procedure used to separate plasma from whole blood. It has been used to treat patients with a variety of chronic diseases involving exchanges of 2.5 L or greater. Given the large volume, when plasmapheresis is used to treat a medical condition, once the plasma is separated from whole blood, the blood can be returned to the body along with r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/34A61M1/36A61M1/38A61K35/14A61K35/16
CPCA61M1/3496A61M1/3621A61M1/3693A61M1/38A61M2210/12A61M2205/75A61K35/16A61K35/14A61P3/00A61P3/06A61P7/00A61P7/08A61P9/00A61K45/06A61M1/34
Inventor 维克托·基立福卢卡斯维克托·基立福罗拉
Owner GRIFOLS
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