Array round biological membrane

Abstract

The invention provides an array of circular biofilms, including an elastic layer and a drug layer from the inside to the outside, the elastic layer is a dense biofilm that can be degraded or absorbed, and the material of the drug layer is biocompatible with human bone biodegradable or Non-degradable, absorbable or non-absorbable porous material, the inside of the drug layer is also encapsulated with drugs that can promote bone healing, the shape of the biofilm is a structure in which unit biological particles are arranged in an array, each unit biological The bottom of the particles is 3-5 mm apart from each other. The biological microstructure membrane is a strip-shaped folded structure with a "U"-shaped cross-section. The inner part is an elastic layer and the outer part is a drug layer. The "U"-shaped cross-section The ratio of width to depth is 0.5‑1.5, where the width is the gap between broken bone surfaces that are spliced ​​together after fracture surgery.

Description

technical field [0001] The present invention relates to an array circular biofilm. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, and prevents the reaction of human tissue on the gr...

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together

[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

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