Cell cryopreservation device for biological 3D printing and method thereof

A 3D printing and storage device technology, applied in the fields of mechanical engineering and biological 3D printing, can solve problems such as frostbite and liquid nitrogen, and achieve the effects of weight reduction, heat exchange reduction, and small volume

Active Publication Date: 2018-10-12
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] This solution requires manual removal or immersion of the cell cryopreservation tubes from liquid nitrogen. Improper handling during the access process may easily cause liquid nitrogen to be stained on the body, causing frostbite and other hazards.

Method used

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  • Cell cryopreservation device for biological 3D printing and method thereof
  • Cell cryopreservation device for biological 3D printing and method thereof
  • Cell cryopreservation device for biological 3D printing and method thereof

Examples

Experimental program
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Embodiment Construction

[0032] The present invention will be further described below in conjunction with the embodiments and the accompanying drawings.

[0033] Such as Figure 1-4 As shown, a cell cryopreservation device for biological 3D printing of the present invention includes a case body 1, a case cover 12 connected to the case body 1 and an access device located in the case body 1; the access device includes Cell cryopreservation tube 5, storage turntable 6, ratchet 7, driving pawl 8, driving swing rod 9, driving push rod 10, stop pawl 11, fixed rod 13, support structure 14, connecting rod 15, ejector rod 16 and torsion spring 21;

[0034] The bottom of the support structure 14 is fixedly connected to the box body 1, and the top is rotatably connected to the center of the ratchet 7; the storage turntable 6 is installed on the ratchet 7 and the two are coaxial, and the storage turntable 6 is provided with round holes arranged uniformly in a circle , the cell cryopreservation tube 5 is placed ...

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PUM

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Abstract

The invention discloses a cell cryopreservation device for biological 3D printing and a method thereof. The cell cryopreservation device comprises a box body, a box cover connected with the box body and a preserving device located in the box body; and the preserving device comprises cell cryopreservation large tubes, a preserving rotation disc, a ratchet wheel, a driving pawl, a driving swinging rod, a driving pushing rod, a locking pawl, a fixing rod, a supporting structure, a connecting rod, an ejection rod and a torsion spring. The cell cryopreservation device is small in size and low in weight, is modularized and can be installed on a portable 3D printer, the heavy defect of an existing preserving device is improved, the safety and convenience of the preserving link are improved, a low-temperature environment capable of preserving cells for a long time is created, and the cell cryopreservation device is suitable for motorized application places.

Description

technical field [0001] The invention belongs to the technical fields of mechanical engineering and biological 3D printing, and specifically relates to a portable cell freezing storage device and method thereof for biological 3D printing Background technique [0002] For the treatment of human damaged skin, different treatment plans are adopted according to the wound area. If the wound is small, direct bandaging or autologous transplantation is usually used clinically; if the wound is large, allografting is usually used. [0003] Self-healthy skin grafts can cause skin loss in critically ill patients, causing secondary damage; while skin donations can trigger immune rejection. Therefore, using the patient's own cells and biomaterials to print out artificial skin for the treatment of skin injuries has received extensive attention. [0004] The existing solutions for cell storage for 3D bioprinting are generally stored in large liquid nitrogen tanks or refrigerators, placed i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B65D25/02B65D25/38B65D81/18B65D81/38A01N1/02
CPCA01N1/0268B65D25/02B65D25/38B65D81/18B65D81/3886
Inventor 张斌李斌捷李嘉程陈旺李佳雨马梁罗熠晨
Owner ZHEJIANG UNIV
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