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A non-invasive blood glucose detection method and system based on electrocardiographic signals

An electrocardiographic signal and blood glucose detection technology, which is applied in the field of non-invasive blood glucose detection methods and systems based on electrocardiographic signals, can solve the problems of low signal-to-noise ratio of the non-invasive method, high cost of the blood glucose detection method, difficult data processing, etc., and achieves low cost. , The effect of low algorithm complexity and small amount of calculation

Active Publication Date: 2019-12-31
PEKING UNIV SHENZHEN GRADUATE SCHOOL
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem mainly solved by the present invention is that the existing blood glucose detection method is invasive and costly, and the non-invasive method has the problems of low signal-to-noise ratio and difficult data processing

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  • A non-invasive blood glucose detection method and system based on electrocardiographic signals
  • A non-invasive blood glucose detection method and system based on electrocardiographic signals
  • A non-invasive blood glucose detection method and system based on electrocardiographic signals

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Embodiment 1

[0021] Embodiment 1 of the present invention: Please refer to figure 1 , a non-invasive blood glucose detection method based on electrocardiographic signals, which includes steps A000 to A100, specifically described below:

[0022] A000: Obtain the ECG signal of the person to be detected.

[0023] A100: Calculate the corresponding blood sugar value according to the electrocardiographic signal.

[0024] In one embodiment, step A100 includes: calculating one or more characteristic indexes of the electrocardiographic signal according to the electrocardiographic signal, and calculating a corresponding blood glucose value according to the characteristic indexes of the electrocardiographic signal.

[0025] In one embodiment, the characteristic index of the ECG signal includes: linearly analyzing the pRRx sequence of the ECG signal to obtain one or more linear characteristic indexes, and / or performing nonlinear analysis to obtain one or more Non-linear feature metrics. The pRRx se...

Embodiment 2

[0056] Embodiment 2: A kind of non-invasive blood sugar detection system based on ECG signal, such as image 3 As shown, including the ECG signal acquisition device B00 and the processor B10, the specific description is as follows:

[0057] The electrocardiographic signal collection device B00 is used to collect the electrocardiographic signal of the person to be detected;

[0058] The processor B10 is configured to execute the ECG signal-based non-invasive blood glucose detection method described in any one of the above embodiments. For example, the processor B10 may calculate one or more characteristic indexes of the electrocardiographic signal according to the electrocardiographic signal, and calculate a corresponding blood sugar value according to the characteristic indexes of the electrocardiographic signal. On the other hand, the processor B10 can pre-establish a model function of the corresponding relationship between the characteristic index of the ECG signal and the ...

Embodiment 3

[0059] Embodiment 3: A kind of non-invasive blood sugar detection product C00 based on electrocardiographic signal, such as Figure 4 As shown, including the memory C01 and the processor C02, the following details:

[0060] Memory C01, used to store programs;

[0061] The processor C02 is configured to execute the program stored in the memory to implement the ECG signal-based non-invasive blood glucose detection method described in any of the above embodiments. For example, the processor C02 executes the program stored in the memory C01, and can calculate one or more characteristic indexes of the electrocardiographic signal according to the characteristic indexes of the electrocardiographic signal, and calculate the corresponding blood sugar value according to the characteristic indexes of the electrocardiographic signal. On the other hand, the program stored in the memory C01 can also be used to pre-establish the model function of the corresponding relationship between the c...

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Abstract

Disclosed in the present invention are an electrocardiosignal-based non-invasive blood glucose detection method and system. The present invention obtains corresponding characteristic indexes by acquiring electrocardiosignals, acquiring a pRRx sequence corresponding to the electrocardiosignals and performing linear analysis and / or non-linear analysis on the pRRx sequence, and obtains a model function of the corresponding relationship between the characteristic indexes of the electrocardiosignals and corresponding blood glucose values by performing machine learning and training using the calculated characteristic indexes and the blood glucose values as inputs and labels; and when the blood glucose value at a certain time point is to be detected, obtains the blood glucose value at the time point by means of the model function by acquiring the electrocardiosignals before the time point, and calculating and in accordance with the characteristic indexes of the electrocardiosignals. Compared with the prior art, the present invention is low in cost and is safe and effective by non-invasively acquiring the electrocardiosignals as source signals; in addition, the calculation amount in the blood glucose detection process of the present method is less, the algorithm complexity is low, and the efficiency is high.

Description

technical field [0001] The invention relates to the technical field of non-invasive blood sugar detection, in particular to a non-invasive blood sugar detection method and system based on electrocardiographic signals. Background technique [0002] There are currently two mainstream blood sugar self-testing methods, invasive and minimally invasive. [0003] Invasive and invasive blood glucose monitoring methods require a blood glucose meter, lancets and blood glucose test strips. The main principle is to measure blood sugar by measuring the current generated by the reaction of glucose in the blood with glucose dehydrogenase or glucose oxidase in the test paper. The advantage of this method is that the measurement results are more accurate. The disadvantage is that the dehydrogenase is not unitary to glucose and is prone to false blood sugar; the oxidase is unitary to glucose, but it is easily oxidized to affect the measurement results. At the same time, this invasive detect...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16H50/70
CPCA61B5/14532A61B5/72A61B5/318A61B5/02405A61B5/0245
Inventor 李冉王新安刘彦伶赵天夏李秋平孙贺陈红英何春舅
Owner PEKING UNIV SHENZHEN GRADUATE SCHOOL