Sealed breathing mask for rat

A breathing mask, sealed technology, applied in medical science, veterinary instruments, etc., can solve the problems of photoacoustic and thermoacoustic image quality deterioration, achieve compact structure, reduce breathing dead space, enhance compatibility and sealing The effect of reliability

Active Publication Date: 2018-10-19
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, when performing photoacoustic and thermoacoustic imaging, the scanning part of the rat needs to be completely immersed in water to be detected by the ultrasonic probe. When scanning the brain of a rat, in order to ensure that the rat can breathe, the rat can only be placed Outside the water, the signal detection is done through the thin film and ultrasonic coupling agent, and the thin film and ultrasonic coupling agent will refract, scatter and absorb laser light, microwave and ultrasonic waves, which will deteriorate the quality of the obtained photoacoustic and thermoacoustic images

Method used

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  • Sealed breathing mask for rat
  • Sealed breathing mask for rat
  • Sealed breathing mask for rat

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0027] 1. Anesthesia: 3% sodium pentobarbital (40-50 mg / kg) was injected intraperitoneally or the rat was placed in a 4% concentration isoflurane induction box for gas induction anesthesia.

[0028]2. Hair removal: If the imaging technology used needs to remove part of the hair (such as: photoacoustic, thermoacoustic and ultrasonic imaging), it is necessary to remove the long hair with a special shaver for small animals in the designated area, and then use depilatory cream to remove it. Short and fluffy. (If it is necessary to ensure 100% air tightness, it is necessary to remove the hair in the contact area between the face of the rat and the special-shaped silicone sealing ring with a shaver, so as to ensure that the special-shaped silicone sealing ring 2 is in contact with the skin of the rat's face).

[0029] 2. Connect the gear bar 3 and the exhaust gas recovery tank (such as activated carbon recovery tank) with a silicone tube to ensure that the experimenter will not come...

specific Embodiment approach 2

[0034] With the help of the invention, a new living rat imaging method based on photoacoustic and thermoacoustic technology can be realized. Compared with the specific implementation mode one, the specific implementation mode two has differences in the method of conducting research on point 5, and the specific implementation mode is:

[0035] 1. The rat wearing the present invention can be installed on the corresponding rat holder through the circular positioning groove 7 of the present invention.

[0036] 2. After adjusting the posture of the rat through the rat fixer, put the whole fixer directly into the coupling medium for photoacoustic and thermoacoustic imaging scanning, which can satisfy the requirements of photoacoustic and thermoacoustic imaging experiments after the rat dives into the water. Experimental requirements to ensure its free breathing.

[0037] Compared with the existing photoacoustic and thermoacoustic methods that only have thin films and ultrasonic cou...

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Abstract

The invention discloses a sealed breathing mask for a rat, and relates to an animal experimental device, in particular to a breathing mask for a rat. The sealed breathing mask for the rat aims to effectively fix the head of the rat and prevent leakage of gas in the mask. The sealed breathing mask for the rat consists of a special-bowl-shaped shell, a special-shaped silica gel sealing ring, a toothed rod, a silica gel ring and a packing ring. By combination of the special-bowl-shaped shell and the silica gel sealing ring, the mask can be attached to the face of the rat, while being connected with the rat and the breathing mask, the toothed rod can further serve as a gas outlet channel of the mask, and while the packing ring can effectively fix the toothed rod, a gas outlet can be sealed bythe packing ring. By good airtightness, an experimenter can be effectively prevented from being exposed in dangerous gas, gas (liquid) of the outside is prevented from entering the mask, experiments such as photoacoustic imaging and thermoacoustic imaging can be met, and after the rat submerges into water, experimental requirements for guaranteeing free breathing of the rat can further be met.

Description

technical field [0001] The invention relates to an animal experiment device, in particular to a rat breathing mask. Background technique [0002] In medical and life science research, respiratory masks, as an important device in rat experiments, have been widely used in experiments such as inhalation anesthesia, inhalation drug delivery, and exposure to oropharyngeal smoke. Existing rat breathing masks are mainly developed for brain stereotaxic instruments, MRI and other equipment. Usually, the rat's teeth are placed on the rack, and the conical (or cylindrical) suction mask is moved backward until it clings to the mouth. Go around the rat's nose or press down the rat's nose by moving the fixed block down to fix the rat's head. However, the rat's head is not completely conical, and the animal's face cannot fit the mask completely. In order to prevent harmful leakage of anesthetic gas, a recovery mask is generally designed outside the conical inhalation mask to cooperate wit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/04
CPCA61D7/04
Inventor 赵渊蒋华北葛绍理赵芮
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA
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