A kind of composition and its preparation method and use

A composition, technology of biotin tripeptide, applied in the field of dermatology, can solve problems such as side effects, high price, and scalp irritation

Active Publication Date: 2022-04-22
HANGZHOU TECHDERM BIOLOGICAL PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these products are irritating to the scalp or have side effects, and the price is relatively high

Method used

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  • A kind of composition and its preparation method and use
  • A kind of composition and its preparation method and use
  • A kind of composition and its preparation method and use

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preparation example Construction

[0051] The preparation method of composition provided by the invention comprises steps:

[0052] In the first step, zinc sulfate and pyridoxine hydrochloride are mixed in a citric acid-sodium citrate buffer solution to obtain solution 1;

[0053] In the second step, sodium hyaluronate is mixed with solution 1 to obtain solution 2;

[0054] In the third step, the solution 2 is mixed with the solution 3 to obtain the composition provided by the present invention; the solution 3 is obtained by mixing the polypeptide complex and water.

[0055] In one embodiment of the present invention, the above-mentioned first step is to dissolve the zinc sulfate and pyridoxine hydrochloride of formula quantity in citric acid-sodium citrate buffer solution; The composition of citric acid-sodium citrate buffer solution is lemon acid, sodium citrate, sodium chloride and water for injection.

[0056]In a preferred embodiment of the present invention, the pH of the buffer solution used in the abo...

Embodiment 1

[0080] Gel to prevent hair loss, promote hair growth and protect hair strands

[0081] Its formula is characterized by quality concentration The meter contains the following components: 500ppm copper peptide, 500ppm biotin tripeptide-1, 500ppm acetyl tetrapeptide-3, 500ppm decapeptide-18, 5.0wt% pyridoxine hydrochloride, 5.0wt% zinc sulfate and 5.0wt% hyaluronic acid Sodium acid.

[0082] Its preparation method is as follows:

[0083] Step 1: 5.0wt% pyridoxine hydrochloride and 5.0wt% zinc sulfate were dissolved in citric acid-sodium citrate buffer solution, and sterilized by filtration with a 0.22 μm aqueous filter membrane.

[0084] Step 2: Add 5.0wt% sodium hyaluronate into the sterilized solution in Step 1, stir mechanically for 36 hours, and fully dissolve.

[0085] Step 3: Dissolve 500ppm copper peptide, 500ppm biotin tripeptide-1, 500ppm acetyl tetrapeptide-3, and 500ppm decapeptide-18 in water for injection under the laminar flow hood, filter and sterilize with a 0...

Embodiment 2

[0088] Gel to prevent hair loss, promote hair growth and protect hair strands

[0089] Its formula contains the following components in mass concentration:

[0090] 1ppm copper peptide, 1ppm biotin tripeptide-1, 1ppm acetyl tetrapeptide-3, 1ppm decapeptide-18, 0.01wt% pyridoxine hydrochloride, 0.01wt% zinc sulfate and 0.01wt% sodium hyaluronate.

[0091] Its preparation method is as follows:

[0092] Step 1: 0.01wt% of pyridoxine hydrochloride and 0.01wt% of zinc sulfate are dissolved in citric acid-sodium citrate buffer solution, and sterilized by moist heat.

[0093] Step 2: Add 0.01wt% sodium hyaluronate to the sterilized solution in Step 1, and shake it on a shaker for 12 hours to fully dissolve.

[0094] Step 3: Dissolve 1ppm copper peptide, 1ppm biotin tripeptide-1, 1ppm acetyl tetrapeptide-3, and 1ppm decapeptide-18 in water for injection under the laminar flow hood, filter and sterilize with a 0.22μm water-based filter membrane, 25 Slowly add the polypeptide solutio...

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Abstract

The invention discloses a composition, its preparation method and application. The composition contains pyridoxine hydrochloride, zinc sulfate, copper peptide, biotin tripeptide-1, acetyl tetrapeptide-3, decapeptide-18 and sodium hyaluronate. The composition provided by the present invention can prevent hair loss, promote hair growth and / or maintain scalp and hair.

Description

technical field [0001] The invention relates to the field of dermatology, in particular to a gel for preventing hair loss, promoting hair growth and protecting hair strands and a preparation method thereof. Background technique [0002] Hair loss is a worldwide skin problem, and about 50% of adult men suffer from hair loss. According to the latest data of the "China Hair Loss Population Survey", there are about 200 million people with hair loss in my country, including about 130 million men with hair loss, and the incidence rate of male hair loss reaches 19.9%. [0003] The most common type of hair loss is "male pattern hair loss", or "androgenic alopecia" or "seborrheic alopecia", accounting for about 95% of the hair loss population. The main reason for male pattern baldness is the stimulation of hair follicles by DHT. In addition to androgenic alopecia, hair loss types also include alopecia areata, mental alopecia, endocrine disorder alopecia, nutritional metabolic alope...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/67A61K8/27A61K8/04A61K8/64A61P17/14A61Q5/12A61Q7/00
CPCA61K8/673A61K8/27A61K8/64A61K8/735A61K8/042A61Q7/00A61Q5/12A61P17/14
Inventor 郝峰柴小华
Owner HANGZHOU TECHDERM BIOLOGICAL PROD CO LTD
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