Method for predicting platinum chemosensitivity of ovarian cancer patient by combining serum glycosylation modification with CA125
A CA125, glycosylation technology, applied in the biological field, can solve problems such as markers that have not yet been found, and achieve the effect of improving the survival rate
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment Construction
[0023] 1) Collect serum samples from ovarian cancer patients before treatment. One year after the end of the platinum-based chemotherapy regimen, 16 patients relapsed within half a year after the completion of platinum-based chemotherapy, and they were chemotherapy-resistant patients; 48 patients relapsed after half a year, and they were chemotherapy-sensitive patients.
[0024] 2) According to the test procedure described in the content of the invention above, detect the glycosylation modification of the patient's serum, calculate the relative expression of á2,3 sialic acid type N-glycan chains, combine the serum CA125 content of the patient, and use SPSS software to perform binary logistic Regression analysis to obtain predicted probabilities.
[0025] 3) With 0.24 as the critical value, if the predicted probability is greater than 0.24, it is classified as a chemoresistant group, and if it is less than 0.24, it is classified as a chemosensitive group.
[0026] 4) When 0.24...
PUM
Property | Measurement | Unit |
---|---|---|
Sensitivity | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com