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Full-automatic mycobacterium tuberculosis microscanning analyzer

A Mycobacterium tuberculosis, fully automatic technology, applied in the field of biomedical testing instruments, can solve the problems of high probability of bacterial infection, difficult to improve work efficiency, and high labor intensity of doctors, so as to avoid bacterial infection, reduce labor intensity, and scan speed. quick effect

Pending Publication Date: 2020-06-12
EAST CHINA NORMAL UNIV +1
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Problems solved by technology

The national detection standard requires 300 effective counts in the field of view, which is very time-consuming and labor-intensive
In the prior art, the microscopic detection of tuberculosis samples is mainly carried out by doctors in the laboratory, through manual observation of optical instruments and microscopes. The existing problems are that the labor intensity of doctors is high, the probability of being infected by germs is high, and the work efficiency is difficult to improve

Method used

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  • Full-automatic mycobacterium tuberculosis microscanning analyzer
  • Full-automatic mycobacterium tuberculosis microscanning analyzer
  • Full-automatic mycobacterium tuberculosis microscanning analyzer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0047] The invention works like this:

[0048] refer to figure 1 , figure 2 , image 3 , Figure 4 , Figure 7 , the doctor will number the slide samples to be tested that have been smeared and put them into the slide grid 31 of the slide rack 3 in sequence, and input the numbering information into the computer 7, and then the present invention will perform the test on the slide samples to be tested. Fully automatic inspection.

[0049] Taking and returning films:

[0050] refer to figure 1 , image 3 , first, the first three-dimensional driving power head 21 of the film transport device 2 is controlled by the computer 7 to control the PLC programmable controller to work, and the first three-dimensional driving power head 21 transports the chuck 51 on the chuck mechanism 5 to the slide rack 3 Corresponding to the position of the slide grid 31, and instruct the clamp drive head 52 on the clamp mechanism 5 to work, so that the clamp mouth 51 clamps the slide sample to b...

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Abstract

The invention discloses a full-automatic mycobacterium tuberculosis microscanning analyzer which comprises a rack, a slide conveying device, a slide rack, a scanning device, a nozzle clamping mechanism, an optical instrument, a computer and an oil injection system; according to the invention, the slide conveying device is adopted to realize extraction and storage of slide samples between the sliderack and the objective table; a scanning device is adopted to accurately send the sample to a detection position specified by an optical instrument, and microscopic scanning is carried out; a computer and a PLC (Programmable Logic Controller) are used for controlling a first three-dimensional driving power head, a second three-dimensional driving power head and a clamping nozzle driving head to operate and controlling switching of a fluorescence switcher on a fluorescence-Candida mechanism, realizing scanning of Ziehl-Neelsen acid-fast staining and fluorescence staining slides, and operational analysis of microscopic images is performed by adopting a computer and a CPU (Central Processing Unit) to finish full-automatic microscopic scanning work of a detected slide sample. The full-automatic mycobacterium tuberculosis microscanning analyzer has the advantages of high automation degree, large slide rack capacity and high image scanning precision.

Description

technical field [0001] The invention relates to the technical field of biomedical detection instruments, which is used for automatic detection of samples of infectious diseases, in particular to a fully automatic tubercle bacillus microscanning analyzer. Background technique [0002] Tuberculosis, caused by Mycobacterium tuberculosis, is a highly contagious disease and one of the top ten causes of death worldwide. The current detection methods for tuberculosis mainly use Ziehl-Neelsen acid-fast staining or fluorescent staining, and then detect under an optical microscope. Mycobacterium tuberculosis is rod-shaped, with a width of 0.3-0.6 microns and a length of 0.5-8 microns (mostly 1.5-3.5 microns). The national detection standard requires 300 effective counts in the field of view, which is very time-consuming and labor-intensive. In the prior art, the microscopic detection of tuberculosis samples is mainly carried out by doctors in the laboratory, through manual observati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01G01N21/84G02B21/00G02B21/24G02B21/36
CPCG01N21/01G01N21/84G02B21/002G02B21/0076G02B21/248G02B21/36
Inventor 刘洪英闫举鹏宋洪成王磊庄泉洁严斯能
Owner EAST CHINA NORMAL UNIV
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