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Reagent combination and kit for detecting blood transfusion transmitted pathogens and application

A technology of pathogens and kits, applied in the field of medical testing, can solve problems such as low prevalence, affecting highly vulnerable groups, and low blood safety correlation

Pending Publication Date: 2020-06-16
山西国际旅行卫生保健中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although some highly pathogenic pathogens may have low prevalence or be limited by seasonal or geographical factors, the correlation with blood safety is not strong
However, transfusion-transmitted infections of blood products can affect highly vulnerable populations such as newborns, the elderly, or the immunocompromised, with fatal consequences

Method used

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  • Reagent combination and kit for detecting blood transfusion transmitted pathogens and application
  • Reagent combination and kit for detecting blood transfusion transmitted pathogens and application
  • Reagent combination and kit for detecting blood transfusion transmitted pathogens and application

Examples

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Embodiment

[0035] The following examples are used herein to demonstrate preferred embodiments of the invention. It should be appreciated by those of skill in the art that the techniques disclosed in the examples which follow represent techniques discovered by the inventors to be employed in the practice of the invention, and thus can be considered preferred modes for its practice. However, those skilled in the art should understand from this specification that many modifications can be made to the specific embodiments disclosed herein, and the same or similar results can still be obtained without departing from the spirit or scope of the present invention.

[0036] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this invention belongs, and the disclosures cited herein and their cited materials are all incorporated by reference .

[0037] Those skilled in the art will recognize, or ...

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PUM

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Abstract

The invention discloses application of a reagent combination for detecting pathogens in preparation of a kit for detecting the quality of a blood product. The pathogens are selected from a pathogen group consisting of HAV, HBV, HCV, HEV, TP, HIV1, HIV2, HTLV1, HTLV2, HBOV, TTV, HCMV, B19, DENV, ZIKV, WNV, babesia, trypanosoma krusei and plasmodium, and belongs to the field of medical examination.The invention further discloses a corresponding kit and a method for detecting the quality of the blood product. By means of the kit, the lowest detection limit of pathogens is 1.0 * 10 < 3 > copies / mL, the kit has good specificity and repeatability, and an important technology is provided for screening and evaluating blood transfusion transmitted pathogens.

Description

technical field [0001] The invention belongs to the field of medical testing, and in particular relates to a reagent combination, kit and application for detecting blood transfusion pathogens. Background technique [0002] According to the "Regulations on the Administration of Health and Quarantine of Entry-Exit Special Articles", special articles entering or exiting the country include microorganisms, human tissues, biological products, blood and their products, etc. Pathogens may be carried, and some special items are pathogens themselves. If effective health and quarantine control is not carried out, special items entering or leaving the country may cause the spread of infectious diseases or other public health hazards. It is becoming more and more important and urgent to explore and study how to carry out scientific and effective health quarantine on special entry and exit items. At present, only environmental protection microorganisms have been tested for compliance wi...

Claims

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Application Information

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IPC IPC(8): C12Q1/70C12Q1/689C12Q1/6893C12Q1/6851C12Q1/06C12R1/93C12R1/90C12R1/01
CPCC12Q1/706C12Q1/707C12Q1/705C12Q1/703C12Q1/701C12Q1/689C12Q1/6893C12Q1/6851C12Q2600/166C12Q2600/16C12Q2531/113C12Q2545/101C12Q2563/107C12Q2537/143Y02A50/30
Inventor 王红李君萍李晓宾杨玉
Owner 山西国际旅行卫生保健中心
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