Novel coronavirus COVID-2019 detection card and preparation method thereof

A technology for COVID-2019 and coronavirus, which is applied in the field of immune detection, can solve problems such as the impact of detection results, and achieve the effects of eliminating inaccurate test results, increasing accuracy, and optimizing marker detection

Pending Publication Date: 2020-07-31
北京乐普诊断科技股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The present invention aims at the deficiencies in the prior art, provides a novel coronavirus COVID-2019 detection card and a preparation method, solves the problem that the above-mentioned interfering substances affect the detection results of the novel coronavirus COVID-2019, and improves the detection rate of the novel coronavirus COVID-2019. detection accuracy

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  • Novel coronavirus COVID-2019 detection card and preparation method thereof
  • Novel coronavirus COVID-2019 detection card and preparation method thereof
  • Novel coronavirus COVID-2019 detection card and preparation method thereof

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preparation example Construction

[0058] The embodiment of the present invention also provides a method for preparing the above-mentioned novel coronavirus COVID-2019 test card, which includes the following steps:

[0059] (11) Choose a plastic material with a smooth surface, non-conductive, non-permeable and absorptive to the sample as the supporting card layer 6 of the test paper 5. The plastic material can be PET, PVC, PE, PP, PS, ABS, hard Metal and the like are preferably PVC, and the thickness of the toca layer 6 is 10 to 1000 μm, preferably 200 to 500 μm. The length of the card layer 6 ranges from 1 to 100 mm, and the width ranges from 1 to 20 mm; preferably, the length ranges from 10 to 50 mm and the width ranges from 4 to 10 mm.

[0060] (12) The pretreatment unit 8 and the sample unit 7 are attached to the pallet layer 6 by gluing, coating or other methods and rolled; to ensure that the functional units and the pallet layer 6 are firmly attached, the cross-cut method can be used to detect Ensure that the...

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Abstract

The invention discloses a novel coronavirus COVID-2019 detection card and a preparation method thereof. The novel coronavirus COVID-2019 detection card comprises a card supporting layer attached to detection test paper, a sample unit positioned on the card supporting layer, a preprocessing unit positioned on the card supporting layer, a marker unit positioned on the card supporting layer, a detection unit positioned on the card supporting layer, and a recycling unit positioned on the card supporting layer; the sample units correspond to the sample holes; the pretreatment unit corresponds to the pretreatment hole; a hollow or transparent sealed detection window is arranged at the position, corresponding to the detection unit, of the shell; the erythrocyte agglutination layer is provided with erythrocyte agglutinin; the endogenous interfering substance treatment layer is provided with an endogenous interfering substance conjugate; the exogenous interfering substance treatment layer is provided with an exogenous interfering substance chelating agent; a non-specific IgM antibody treatment layer is provided with an IgM chelating agent; a non-specific IgG antibody treatment layer has anIgG precipitant. The problem that interfering substances influence the detection result of the novel coronavirus is solved, and the detection accuracy is improved.

Description

Technical field [0001] The invention relates to a new type of coronavirus COVID-2019 detection card and a preparation method thereof, and belongs to the technical field of immune detection. Background technique [0002] Coronavirus is a single-stranded positive-stranded RNA virus with an envelope, which can cause major diseases such as colds, Middle East Respiratory Syndrome (MERS) and severe acute respiratory syndrome (SARS). 2019-nCoV was officially named by the World Health Organization on January 12, 2020. The core protein of 2019-nCoV is the N protein (Nucleocapsid), which is located inside the virus. It is relatively conservative among β-coronaviruses and is often used for coronavirus detection. The transmission route of the new coronavirus COVID-2019 is still respiratory droplet transmission and contact transmission. The transmission routes of aerosol and feces-oral still need to be further clarified. Therefore, choosing an appropriate method for the detection of the new...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/569G01N33/543
CPCG01N33/56983G01N33/54313G01N2333/165
Inventor 李文娜胡飞邱笑违董飒英
Owner 北京乐普诊断科技股份有限公司
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