Curved chromosome image straightening method and system based on BagPix2Pix self-learning model, storage medium and device

A chromosome, self-learning technology, applied in image enhancement, image analysis, image data processing and other directions, can solve problems such as straightening, failure to meet usage requirements, discontinuous chromosome information, etc., to achieve high accuracy, improve integrity and continuity The effect of high stability and high classification accuracy

Pending Publication Date: 2020-09-01
XIAN JIAOTONG LIVERPOOL UNIV +1
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Problems solved by technology

This method is suitable for chromosomes with only one large bend, but chromosome photos taken in different experiments and fineness often have three or more bends, so this algorit

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  • Curved chromosome image straightening method and system based on BagPix2Pix self-learning model, storage medium and device
  • Curved chromosome image straightening method and system based on BagPix2Pix self-learning model, storage medium and device
  • Curved chromosome image straightening method and system based on BagPix2Pix self-learning model, storage medium and device

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Embodiment Construction

[0050] Objects, advantages and features of the present invention will be illustrated and explained by the following non-limiting description of preferred embodiments. These embodiments are only typical examples of applying the technical solutions of the present invention, and all technical solutions formed by adopting equivalent replacements or equivalent transformations fall within the protection scope of the present invention.

[0051]In the description of the scheme, it should be noted that the terms "center", "upper", "lower", "left", "right", "front", "rear", "vertical", "horizontal", " The orientation or positional relationship indicated by "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of description and simplification of description, rather than indicating or implying that the device or element referred to must have a specific orientation , constructed and operated in a particular ori...

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Abstract

The invention discloses a curved chromosome image straightening method and system, based on a BagPix2Pix self-learning model, a storage medium and a device. The method comprises the following steps: S1, receiving a curved chromosome original image, and processing the curved chromosome original image to obtain a mark image; S2, generating a chromosome skeleton anchor point graph according to the marker image obtained in the step S1; S3, generating a chromosome straightening skeleton diagram according to the chromosome skeleton anchor point diagram; and S4, inputting the chromosome straighteningskeleton diagram into a curved chromosome image straightening model which is trained to be convergent and can receive a prediction diagram which can be output and matched by the skeleton diagram, andgenerating a curved chromosome straightening image. Compared with an existing method based on iconography, the method has the advantages that the result of the method does not contain obvious fractures and sections, the quality of the straightened chromosome image and the integrity and continuity of effective features are greatly improved, the method is not affected by the number of curves and curved parts, and the accuracy is high.

Description

technical field [0001] The invention relates to the technical field of image processing, and specifically relates to a method, system, storage medium and device for straightening a curved chromosome image based on a BagPix2Pix self-learning model. Background technique [0002] With the development of computer technology and artificial intelligence, the recognition and segmentation of images through computer algorithms can be preliminarily realized, and image analysis technology is generally used in medicine for the detection, separation and extraction of objects in medical images. But when the detected object is in different shapes, such as bending and overlapping, graphics algorithms often cannot change the shape of the object at the pixel level. [0003] Human genetic information is carried on chromosomes, so karyotype analysis is the basic method of cytogenetics research, an important means to study the relationship between chromosome shape and structure and its function,...

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Application Information

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IPC IPC(8): G06T7/00G06T7/12G06T7/62G06T5/00
CPCG06T7/0012G06T7/12G06T7/62G06T5/006G06T2207/10064G06T2207/10061G06T2207/30004G06T2207/20084G06T2207/20081
Inventor 苏炯龙马飞孟佳宋思凡黄戴赟时长军肖晟杨春潇
Owner XIAN JIAOTONG LIVERPOOL UNIV
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