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Biological agent for treating myopia as well as preparation method and use method thereof

A biological agent, a technique for myopia

Pending Publication Date: 2020-10-23
重庆康视美科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The above reports only initially revealed the basic role of basic fibroblast growth factor and transforming growth factor-β on the growth of human scleral fibroblasts, how to apply basic fibroblast growth factor and transforming growth factor-β in the treatment of myopia It needs to be further researched. In addition, the above papers did not reveal whether basic fibroblast growth factor and transforming growth factor-β are involved in the physiological function of ciliary muscle

Method used

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  • Biological agent for treating myopia as well as preparation method and use method thereof
  • Biological agent for treating myopia as well as preparation method and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0040] The only difference between Examples 1-3 is that the contents of basic fibroblast growth factor, transforming growth factor and mouse nerve growth factor are different. The content of basic fibroblast growth factor, transforming growth factor and mouse nerve growth factor in the embodiment 1-3 is specifically referred to the following table:

[0041] test group basic fibroblast growth factor transforming growth factor mouse nerve growth factor Example 1 50ug 10ug 5ug Example 2 65ug 20ug 10ug Example 3 80ug 30ug 15ug

[0042] Validity Experiment 1

[0043] Choose 1056 people of myopia patients aged 7-65, divide them into eight groups according to their age groups, use the present invention every day before getting up in the morning (7:00-9:00) and falling asleep at night (21:00-22:00) Biological preparations provided, after 6 months of treatment, count the effective rate and emmetropy rate of the biological preparation...

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Abstract

The invention belongs to the technical field of myopia regulatory diseases, and particularly discloses a biological agent for treating myopia. The biological agent comprises a basic fibroblast growthfactor, 10-30 [mu]g of a transforming growth factor and 5-15 [mu]g of a mouse nerve growth factor, wherein the mass sum of the transforming growth factor and the mouse nerve growth factor is less thanor equal to the mass of the basic fibroblast growth factor, and the mass of the basic fibroblast growth factor is less than or equal to two times the mass sum of the transforming growth factor and the mouse nerve growth factor. The invention also discloses a preparation method and use method of the biological agent for treating the myopia. The biological agent not only can promote self-healing ofthe myopia, but also is high in safety.

Description

technical field [0001] The invention belongs to the technical field of myopia-related accommodative diseases, and in particular relates to a biological preparation for treating myopia, a preparation method and a use method thereof. Background technique [0002] Myopia refers to the state where the eye does not apply the adjustment function. Parallel light rays pass through the refractive system of the eye to form a focus in front of the retina, and then form a scattered and blurred aperture on the retina. This refractive state is called myopia. Myopia can be divided into mild myopia (<300 degrees), moderate myopia (300-600 degrees) and high myopia (>600 degrees). Myopia has rapidly become a global health problem over the past three decades, becoming one of the leading causes of visual impairment and associated with potentially blinding ocular complications including retinal detachment, myopic maculopathy, glaucoma, and cataracts. [0003] Myopia is caused by multiple ...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K9/00A61P27/10
CPCA61K38/1825A61K38/1841A61K38/185A61K9/0048A61P27/10A61K2300/00
Inventor 肖庆兵李金本陈帝江
Owner 重庆康视美科技有限公司
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