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Traditional Chinese medicine composition for inhibiting early development and precocious puberty in children, preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of high price, inhibited growth group, polycystic ovary syndrome, etc., and achieve the effects of inhibiting early development, correcting endocrine and metabolic disorders, and reducing hypergonadism

Active Publication Date: 2022-04-15
上海艾育生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, biological products are mainly used in the treatment of precocious puberty in children. At present, the internationally recognized drug for the treatment of central precocious puberty is gonadotropin-releasing hormone analogue (GnRHa), but it is expensive. Generally, children will develop growth after 3-6 months of application. The group is inhibited, growth hormone must be injected at the same time, and it can also lead to polycystic ovary syndrome. Phytotherapy, can effectively inhibit the hypothalamus-pituitary-gonadal axis hyperactivity

Method used

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  • Traditional Chinese medicine composition for inhibiting early development and precocious puberty in children, preparation method and application
  • Traditional Chinese medicine composition for inhibiting early development and precocious puberty in children, preparation method and application
  • Traditional Chinese medicine composition for inhibiting early development and precocious puberty in children, preparation method and application

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Effect test

Embodiment 1

[0028] The traditional Chinese medicine composition for inhibiting early development and precocious puberty in children comprises: 12.5 parts by weight of sealwort, 12.5 parts by weight of Poria cocos, 12.5 parts by weight of Chinese yam, 7.5 parts by weight of gardenia and 55.0 parts by weight of malt.

[0029] Preparation:

[0030] Weigh the above medicinal materials according to the above ratio, then put them into the extraction tank, spray with water to remove dust, sand and other impurities on the medicinal materials, add water 10 times the amount of all medicinal materials after removing water and impurities, boil and boil for 2 hours , filter to obtain the medicinal solution, add the filter residue to water 6 times the amount of the whole medicinal material again, boil and boil for 1 hour, filter to obtain the medicinal solution, combine the two obtained medicinal solutions, and concentrate the combined medicinal solution into medicinal material: medicinal solution =1 p...

Embodiment 2

[0036] The traditional Chinese medicine composition for inhibiting early development and precocious puberty in children comprises: 20 parts by weight of sealwort, 5 parts by weight of poria cocos, 20 parts by weight of Chinese yam, 3 parts by weight of gardenia and 88 parts by weight of malt.

[0037] Preparation:

[0038] Weigh the above medicinal materials according to the above ratio, then put them into the extraction tank, spray with water to remove dust, sand and other impurities on the medicinal materials, add water 10 times the amount of all medicinal materials after removing water and impurities, boil and boil for 2 hours , filter to obtain the medicinal solution, add the filter residue to water 6 times the amount of the whole medicinal material again, boil and boil for 1 hour, filter to obtain the medicinal solution, combine the two obtained medicinal solutions, and concentrate the combined medicinal solution into medicinal material: medicinal solution =1 part by mass...

Embodiment 3

[0044] The traditional Chinese medicine composition for inhibiting early development and precocious puberty in children comprises: 5 parts by weight of sealwort, 20 parts by weight of poria cocos, 5 parts by weight of Chinese yam, 12 parts by weight of gardenia and 22 parts by weight of malt.

[0045] Preparation:

[0046] The above-mentioned medicinal materials are weighed according to the above-mentioned proportions, and then they are all put into an extraction tank, and impurities such as dust, sand and stones on the medicinal materials are removed by spraying with water. Boil for 2 hours, filter to obtain the medicinal solution, add 70% ethanol that is 6 times the amount of the whole medicinal material to the filter residue again, boil and boil for 1 hour, filter to obtain the medicinal solution, combine the two obtained medicinal solutions, and combine the combined medicinal solution Concentrate under reduced pressure and recover ethanol, and finally concentrate the medic...

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Abstract

The invention provides a traditional Chinese medicine composition for inhibiting children's early development and precocious puberty, its preparation method and application. 12 parts, 22-88 parts of malt; the preparation method is to extract the above-mentioned traditional Chinese medicine composition with water or ethanol, filter through a ceramic membrane after concentration, then use a medium-polarity macroporous adsorption resin column and a polyamide column to adsorb in sequence, and wash with water and then elute with 40%-70% ethanol, collect the eluate, concentrate the eluate under reduced pressure, and then spray-dry the concentrated solution to obtain a fine powder. , precocious puberty medicine and food, the traditional Chinese medicine composition of the present invention can inhibit children's early development and precocious puberty, and has low price and no side effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition for inhibiting children's early development and precocious puberty, a preparation method and an application. Background technique [0002] Early child development and precocious puberty are the occurrence of diseases caused by endocrine disorders when children are affected by abnormal internal and external factors during their development. [0003] According to the notice issued by the Ministry of Health on the trial implementation of the guidelines for the diagnosis of precocious puberty: the age of precocious puberty in children: before the age of 9 for boys and before the age of 8 for girls, secondary sexual characteristics are present. According to the pathogenesis and clinical manifestations, precocious puberty can be divided into central precocious puberty and peripheral precocious puberty, previously known as true pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P5/24A61P25/20A61P19/08A23L2/39A23L2/38A23L33/105A23L33/10
CPCA61K36/8969A61K36/076A61K36/8945A61K36/744A61K36/8998A61P5/24A61P25/20A61P19/08A23L2/39A23L2/38A23L33/105A23L33/10A61K2236/331A61K2236/33A61K2236/53A61K2236/51A61K2236/55A23V2002/00A61K2300/00A23V2200/30A23V2250/208A23V2250/21
Inventor 王珏邵旭
Owner 上海艾育生物科技有限公司
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