Inter-drug adverse reaction early warning method, early warning device and early warning system

Abstract

The invention provides an inter-drug adverse reaction early warning method, early warning device and early warning system, and the early warning method comprises the following steps: constructing a Chinese and Western drug interaction ontology, and storing the constructed Chinese and Western drug interaction ontology in an ontology knowledge base; the Chinese and western medicine interaction ontology comprises a semantic type, an instantiated entity and a semantic relationship; constructing an inference rule based on description logic; the inference rule is constructed based on a corresponding interaction result in the interaction of the Chinese and western medicine types and the medicine components; acquiring a drug name, and acquiring associated information of the drug from the constructed Chinese and western drug interaction ontology; and judging the reactions between the drugs by using the constructed inference rule according to the association information of the drugs, and performing early warning of the adverse reactions between the drugs according to the judgment result. According to the method, the early warning efficiency of the adverse reactions between the drugs can be greatly improved, and the recall ratio and the precision ratio of the adverse reactions between the drugs are improved.

Description

technical field [0001] The application belongs to the field of medical technology, and in particular relates to an early warning method, an early warning device and an early warning system for adverse drug reactions. Background technique [0002] Drugs interaction (DI) refers to the compound effect produced by the patient taking two or more drugs at the same time or successively within a certain period of time, which can enhance the efficacy of the drug or reduce the side effects, or weaken the efficacy of the drug or cause adverse reactions. Some toxic side effects. Enhanced drug efficacy includes increased curative effect and increased toxicity, and weakened drug effect includes decreased curative effect and reduced toxicity. Therefore, when using drug combination clinically, we should pay attention to the characteristics of various drugs and give full play to the pharmacological effects of each drug in the drug combination, so as to achieve the best curative effect and t...

AI Technical Summary

Problems solved by technology

The biggest defect of this traditional method lies in the dependence on individual experience and low efficiency, which are specifically manifested in: 1) For young doctors with insufficient drug knowledge and clinical experience, it is easy to cause adverse reactions in patients due to negligence in medication, resulting in unsatisfactory outcomes. less than expected

2) If it is often necessary to use traditional methods for manual investigation of adverse drug reactions, it is time-consuming, laborious, extremely inefficient and difficult to meet daily needs

3) Even if the query is carried out through the relevant database of adverse drug reactions, there is still a real-time problem. If there are multiple drugs used in combination, the query efficiency is often not high, and there are technical thresholds in use, and it is difficult to meet the actual situation. need

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