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Prescription of remote patient management based on biomarkers

A biomarker, patient technology, applied in the field of medical diagnosis

Pending Publication Date: 2021-09-03
BRAHMS GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Given the prevalence of cardiovascular diseases such as heart failure in modern society, simply assigning remote patient management to any or all patients with cardiovascular disease has the potential to impose considerable financial burden and technical challenges on healthcare providers

Method used

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  • Prescription of remote patient management based on biomarkers
  • Prescription of remote patient management based on biomarkers
  • Prescription of remote patient management based on biomarkers

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0223] The present invention relates to methods for treatment guidance, stratification and / or monitoring of remote patient management of patients who have been diagnosed with cardiovascular disease. As is apparent from the data presented herein, the potential benefit of prescribing telepatient management to patients with cardiovascular disease can be predicted based on levels of proADM, proBNP, and / or proANP, or one or more fragments thereof, thereby providing information on treatment guidance, Valuable information for layers and / or monitoring.

[0224] Compared with conventional methods, the present invention has the following advantages: the method and kit of the present invention are fast, objective, easy to use, reliable and accurate, and can be used for treatment guidance, stratification and / or monitoring for remote patient management. Employing the methods and kits described herein allows for efficient resource allocation when prescribing remote patient management to tho...

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Abstract

The invention relates to a method for determining whether a subject diagnosed with a cardiovascular disease should be prescribed a remote patient management, the method comprising measuring particular biomarkers in a sample from said patient. The invention therefore relates to a method for therapy guidance, stratification and / or monitoring of a remote patient management for a patient diagnosed with a cardiovascular disease, comprising providing at least one sample of a patient, determining a level of at least one biomarker selected from the group consisting of pro ADM, pro BNP and pro ANP or fragment(s) and comparing said level of the at least one biomarker to one or more reference values, wherein said level is indicative of prescribing or not prescribing a remote patient management for said patient. In some embodiments a low benefit level of the at least one biomarker is indicative of not prescribing a remote patient management, whereas in some embodiments a high benefit level of the at least one biomarker is indicative of prescribing a remote patient management. In some embodiments, the cardiovascular disease is heart failure, in particular a chronic heart failure that has led to a hospitalization within the last 12 months.

Description

technical field [0001] The present invention relates to the field of medical diagnosis, in particular, prognosis and treatment guidance based on molecular biomarkers. [0002] The present invention relates to a method for determining whether remote patient management should be prescribed to a subject diagnosed with a cardiovascular disease, the method comprising measuring a specific biomarker in a sample from said patient. Accordingly, the present invention relates to a method for treatment guidance, stratification and / or monitoring of remote patient management of a patient diagnosed with a cardiovascular disease, the method comprising: providing at least one sample of the patient; determining A level of at least one biomarker or one or more fragments thereof of the group consisting of proADM, proBNP, and proANP; and comparing said level of said at least one biomarker to one or more reference values, wherein The level indicates whether remote patient management is prescribed ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/74
CPCG01N33/74G01N2333/58G01N2800/325G01N2800/52G01N33/6893G01N33/70
Inventor T·斯图贝J·维默尔J·坤德S·贾里格F·克勒
Owner BRAHMS GMBH
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