Application of mitochondrial autophagy activator in platelet preservation

A technology for mitophagy and activator, applied in the field of biomedicine, can solve the problem of inability to improve the function of preserved platelets, and achieve the effects of improving the function of preserved platelets, reducing mitochondrial damage and improving the quality of preservation

Pending Publication Date: 2022-06-28
苏天生命科技(苏州)有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, studies over the years have shown that inhibition of the platelet apoptosis pathway, although ...

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  • Application of mitochondrial autophagy activator in platelet preservation
  • Application of mitochondrial autophagy activator in platelet preservation
  • Application of mitochondrial autophagy activator in platelet preservation

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Embodiment Construction

[0029] In order to make the above objects, features and advantages of the present invention more clearly understood, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the connotation of the present invention. Therefore, the present invention is not limited by the specific embodiments disclosed below.

[0030] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terms used herein in the description of the present invention are for the purpo...

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Abstract

The invention discloses an application of a mitochondrial autophagy activator in platelet preservation, and the mitochondrial autophagy activator can be used for improving the platelet preservation function and preparing a platelet preservation additive. Experiments prove that the mitochondrial autophagy activator can effectively reduce mitochondrial damage of platelets in the storage process and improve the function of storing the platelets, and no precedent for effectively improving the function of storing the platelets by using the autophagy activator exists at home and abroad, so that the mitochondrial autophagy activator is expected to be applied to the storage of the platelets. And the method is expected to be used for preparing a platelet preservation additive so as to improve the platelet preservation quality.

Description

technical field [0001] The invention belongs to the field of biomedicine and relates to a new application of a mitophagy activator, in particular to the application of the mitophagy activator in platelet preservation. Background technique [0002] Platelets are the most abundant and smallest cytoplasmic structures in blood, with specific morphological and biochemical compositions. The physiological lifespan of human platelets is about 7-9 days, and it plays an important role in physiological and pathological processes such as hemostasis, wound repair, and inflammatory response. The platelets for clinical component transfusion are basically derived from platelets collected and stored by blood stations in various places. In addition to patients with hypoplatelet disease, with the aging of the population in my country, the continuous increase of cancer radiotherapy patients, and the increase of major surgery cases, the demand for platelet allogeneic transfusion in my country i...

Claims

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Application Information

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IPC IPC(8): A01N1/02
CPCA01N1/0226A01N1/021
Inventor 王建荣李磊方艺璇
Owner 苏天生命科技(苏州)有限公司
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