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Tefu medicine liquid and its prepn

A furfur solution and tinidazole technology, applied in the directions of topical antibacterial agents, heterocyclic compound active ingredients, etc., can solve the problems of poor comprehensive effect of aerobic bacteria and anaerobic bacteria, breeding environment of glucose solution bacteria, etc., to shorten the course of treatment, Improves the level of treatment and eliminates infections

Inactive Publication Date: 2002-12-11
HOSPITAL ATTACHED TO QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims to solve the problems existing in the prior art that the comprehensive effect of killing aerobic bacteria and anaerobic bacteria at the same time is poor and glucose solution becomes a breeding environment for bacteria.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1, proceed as follows: dissolve 10 g of tinidazole, 1 g of nitrofurazone and 40 g of sodium chloride in an appropriate amount of water for injection according to the composition and proportioning range, stir for 10 to 15 minutes, and then add water for injection to the prescribed dosage of 4000 g After the measured pH value meets the range of 4.5-6.5 and the content is qualified, the fine filter tank is sealed, then heated to 110-120°C, and sterilized by heating for 20-40 minutes.

Embodiment 2

[0014] Example 2, proceed as follows: Dissolve 20 g of metronidazole, 1.5 g of nitrofurazone and 45 g of sodium chloride in an appropriate amount of water for injection according to the composition and proportion range, stir for 10 to 15 minutes, and then add water for injection to the specified dosage 5000g, after the measured pH value meets the range of 4.5-6.5 and the content is qualified, the fine filter tank is sealed, then heated to 110-120°C, and sterilized by heating for 20-40 minutes.

Embodiment 3

[0015] Example 3, proceed as follows: dissolve 20 g of tinidazole, 2 g of nitrofurazone and 50 g of sodium chloride in an appropriate amount of water for injection according to the composition and proportioning range, stir for 10 to 15 minutes, and then add water for injection to the prescribed dosage of 6000 g After the measured pH value meets the range of 4.5-6.5 and the content is qualified, the fine filter tank is sealed, then heated to 110-120°C, and sterilized by heating for 20-40 minutes.

[0016] The invention solves the defects that the local application of antibiotics easily causes bacteria, the local washing of glucose solution tends to become a good breeding environment for bacteria, and the single use of nitrofurazone or nitro antibiotics has a narrow antibacterial spectrum, and realizes the ability to resist aerobic bacteria And anaerobic infection, and can not produce bacterial resistance, but also can not provide the conditions for the bacteria to reproduce, so ...

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PUM

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Abstract

The externally applied lotion, named Tifu liquid, for treating aerobic bacteria and anaerobic bacteria infection consists of (in weight portions): Tinidazole 10-20 or Metronidazole 2-30, Furacin 1-2,sodium chloride 40-50 and water for injection 4000-6000. Compared with availble technology, the present invention is superior in that it contains Tinidazole capable of killing anaerobic bacteria, Furacin capable of killing aerobic bacteria and no glucose likely to form condition for bacteria to grow and propagate.

Description

Technical field [0001] The invention relates to a medicine, in particular to an external flushing medicine solution for treating and preventing aerobic bacteria and anaerobic bacteria infection. Background technique [0002] Existing treatment purulent infection wound, the medicine of incision roughly contain following three kinds: 1, nitrofurazone solvent: it is the 0.01%~0.02% solution of local external use, also useful 2% solution. The drug has a wide antibacterial spectrum, no stimulation to tissues, pus and blood have no obvious effect on its disinfection effect, and it is not easy to produce drug resistance, and it can be used for a long time without reducing the effect. 2. Metronidazole: It is a nitro-type synthetic antibiotic. It was identified by WHO as the basic and preferred drug against anaerobic infection in 1978. The metronidazole G injection is 250ml / bottle, containing 0.5g of metronidazole and 12.5 grams of glucose. g. For intravenous injection, there is als...

Claims

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Application Information

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IPC IPC(8): A61K31/43A61P31/02
Inventor 李宁毅贾暮云陈德利綦秀芬荆凡波杨学财
Owner HOSPITAL ATTACHED TO QINGDAO UNIV
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